Huang Fuchun, Yang Shuang, Ma Mingxuan, Zhang Jialin, Liu Hua
Department of Tuberculosis, Hangzhou Red Cross Hospital, Hangzhou, China.
Medical School of Nantong University, Nantong, Jiangsu, China.
Clin Respir J. 2025 Apr;19(4):e70075. doi: 10.1111/crj.70075.
As a disease-modifying strategy, physical exercise has been demonstrated to significantly improve quality of life, exercise capacity, and lung function in individuals with asthma. However, the quality and robustness of this evidence has not been thoroughly examined in many large-scale investigations. In order to assess the evidence addressing the effects of physical exercise in patients with asthma, we therefore carried out an umbrella review.
A comprehensive search of the PubMed, Web of Science, and Cochrane databases for systematic reviews and meta-analyses of the effects of physical activity on asthma was conducted up to December 31, 2022. The study was registered in Prospero (CRD42023382921). For every qualified systematic review and meta-analysis, we extracted information on the main characteristics and general findings. The GRADE tool was utilized to quantify the strength of the evidence, and the AMSTAR2 score was employed to evaluate the methodological quality.
A total of 1254 articles were searched, and 42 independent results were identified as eligible in the 11 articles that were included. Of the 42 unique outcomes, two were rated as high, two as medium, and the rest as low or very low. Physical exercise is beneficial for improving QoL, exercise capacity, and lung function in patients with asthma.
According to our research, physical activity benefits QoL of patients with asthma, exercise tolerance, and lung function. In the future, further evidence from superior prospective studies will be required because the quality of the available evidence is now insufficient.
作为一种改善病情的策略，体育锻炼已被证明能显著提高哮喘患者的生活质量、运动能力和肺功能。然而，在许多大规模调查中，这一证据的质量和可靠性尚未得到充分检验。因此，为了评估有关体育锻炼对哮喘患者影响的证据，我们进行了一项汇总分析。
截至2022年12月31日，对PubMed、科学网和Cochrane数据库进行了全面检索，以查找关于体育活动对哮喘影响的系统评价和荟萃分析。该研究已在国际前瞻性系统评价注册库（CRD42023382921）注册。对于每一项合格的系统评价和荟萃分析，我们提取了主要特征和总体研究结果的信息。使用GRADE工具量化证据的强度，并采用AMSTAR2评分评估方法学质量。
共检索到1254篇文章，在纳入的11篇文章中确定了42项独立结果符合条件。在这42项独特的结果中，两项被评为高等级，两项为中等，其余为低等级或极低等级。体育锻炼有利于改善哮喘患者的生活质量、运动能力和肺功能。
根据我们的研究，体育活动有益于哮喘患者的生活质量、运动耐量和肺功能。由于现有证据的质量目前不足，未来将需要来自更优质前瞻性研究的进一步证据。
