Yang Xiaobin, Cheng Jiangbo, Xu Dan, Li Chong, Zhang Deyin, Zhang Yukun, Huang Kai, Li Xiaolong, Zhao Yuan, Zhao Liming, Xu Quanzhong, Ma Zongwu, Tian Huibin, Weng Xiuxiu, Peng Jie, Zhang Xiaoxue, Wang Weimin
1State Key Laboratory of Herbage lmprovement and Grassland Agro-ecosystems, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs; Engineering Research Center of Grassland Industry, Ministry of Education, Collegeof Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, Gansu, China.
College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
Microbiol Spectr. 2025 Jun 3;13(6):e0142324. doi: 10.1128/spectrum.01423-24. Epub 2025 Apr 17.
Increasing strain on feed resources has led to a gradual increase in feed input costs, making it necessary to improve feed efficiency in livestock and poultry. In this study, Hu sheep were divided into two groups (high and low feed conversion ratio [FCR]) according to the FCR. Based on 16S rDNA amplicon sequencing technology to compare rumen and small intestine microbial composition, the differences and similarities of production performance, expression level of intestinal nutrient-specific carrier, digestive enzyme activity, short-chain fatty acid (SCFA) content, muscle conventional nutrient content, and blood biochemical indexes of Hu sheep in high- and low-FCR groups were investigated, and correlation analysis was conducted. The results showed that Hu sheep in the low-FCR group had higher feed efficiency, average daily gain, and less fat deposition ( < 0.05). The difference in rumen microbial composition between the high- and low-FCR groups was significant ( < 0.05). Spearman's correlation analysis showed that FCR was significantly associated with production performance such as body weight, fat deposition, and dressing percentage ( < 0.05). The levels of digestive enzyme activity and nutrient transporter carrier expression in the small intestine were higher in the low-FCR group than in the high-FCR group. Therefore, FCR can be one of the important targets of concern in Hu sheep production. Combining FCR and regulating the gastrointestinal environment of Hu sheep by nutritional means can greatly improve the production performance and economic benefit of Hu sheep.
Feed costs account for a large portion of housed sheep. The purpose of comparing the performance and intestinal microbial composition of different FCR Hu sheep is to regulate the gastrointestinal microecology in production practice. This helps livestock producers choose low-FCR Hu sheep to maximize production costs, improve efficiency, and achieve the purpose of low-carbon production.
饲料资源压力的增加导致饲料投入成本逐渐上升，因此有必要提高畜禽的饲料效率。在本研究中，根据饲料转化率（FCR）将湖羊分为两组（高FCR组和低FCR组）。基于16S rDNA扩增子测序技术比较瘤胃和小肠微生物组成，研究了高FCR组和低FCR组湖羊的生产性能、肠道营养特异性载体表达水平、消化酶活性、短链脂肪酸（SCFA）含量、肌肉常规营养成分和血液生化指标的差异与相似性，并进行了相关性分析。结果表明，低FCR组湖羊具有更高的饲料效率、平均日增重和更少的脂肪沉积（<0.05）。高FCR组和低FCR组瘤胃微生物组成差异显著（<0.05）。Spearman相关性分析表明，FCR与体重、脂肪沉积和屠宰率等生产性能显著相关（<0.05）。低FCR组小肠消化酶活性和营养转运载体表达水平高于高FCR组。因此，FCR可作为湖羊生产中重要的关注指标之一。结合FCR并通过营养手段调节湖羊的胃肠道环境，可大大提高湖羊的生产性能和经济效益。
饲料成本占舍饲绵羊成本的很大一部分。比较不同FCR湖羊的性能和肠道微生物组成的目的是在生产实践中调节胃肠道微生态。这有助于畜牧生产者选择低FCR湖羊，以最大限度地降低生产成本、提高效率并实现低碳生产的目的。
