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1
Assessing the Impact of Asthma: A Cross-Sectional Study in Workers Undergoing Therapy.评估哮喘的影响:一项针对正在接受治疗的工人的横断面研究。
Med Lav. 2025 Apr 17;116(2):15786. doi: 10.23749/mdl.v116i2.15786.
2
The impact of poor asthma control among asthma patients treated with inhaled corticosteroids plus long-acting β-agonists in the United Kingdom: a cross-sectional analysis.英国接受吸入皮质类固醇加长效β激动剂治疗的哮喘患者中哮喘控制不佳的影响:一项横断面分析。
NPJ Prim Care Respir Med. 2017 Mar 9;27(1):17. doi: 10.1038/s41533-017-0014-1.
3
Burden of asthma among patients adherent to ICS/LABA: A real-world study.吸入性糖皮质激素/长效β2受体激动剂(ICS/LABA)依从性患者的哮喘负担:一项真实世界研究。
J Asthma. 2019 Mar;56(3):332-340. doi: 10.1080/02770903.2018.1455858. Epub 2018 Apr 6.
4
Asthma control in patients treated with inhaled corticosteroids and long-acting beta agonists: A population-based analysis in Germany.吸入性糖皮质激素和长效β受体激动剂治疗患者的哮喘控制:德国一项基于人群的分析。
Respir Med. 2016 Sep;118:58-64. doi: 10.1016/j.rmed.2016.07.012. Epub 2016 Jul 16.
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Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma.长效β2受体激动剂与抗白三烯药物加用吸入性糖皮质激素治疗慢性哮喘的比较
Cochrane Database Syst Rev. 2014 Jan 24;2014(1):CD003137. doi: 10.1002/14651858.CD003137.pub5.
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Adherence to inhaled corticosteroids and long-acting β2-agonists in asthma: A MASK-air study.哮喘患者吸入性糖皮质激素和长效β2受体激动剂的依从性:一项MASK-air研究。
Pulmonology. 2025 Dec 31;31(1):2416869. doi: 10.1016/j.pulmoe.2023.07.004. Epub 2024 Oct 25.
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Combination of inhaled long-acting beta2-agonists and inhaled steroids versus higher dose of inhaled steroids in children and adults with persistent asthma.吸入长效β2受体激动剂与吸入性糖皮质激素联合使用与高剂量吸入性糖皮质激素治疗儿童和成人持续性哮喘的比较
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Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma.长效β2受体激动剂与抗白三烯药物联合吸入糖皮质激素治疗慢性哮喘的比较
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Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children.福莫特罗与布地奈德联合用于成人和儿童慢性哮喘的维持和缓解治疗与当前最佳实践(包括吸入性糖皮质激素维持治疗)的对比研究
Cochrane Database Syst Rev. 2013 Apr 30;2013(4):CD007313. doi: 10.1002/14651858.CD007313.pub3.
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Interventions to improve adherence to inhaled steroids for asthma.改善哮喘患者吸入性糖皮质激素依从性的干预措施。
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本文引用的文献

1
Global Initiative for Asthma Strategy 2021. Executive Summary and Rationale for Key Changes.《2021年全球哮喘防治创议策略》。执行摘要及关键变化的理论依据。
Arch Bronconeumol. 2022 Jan;58(1):35-51. doi: 10.1016/j.arbres.2021.10.003. Epub 2021 Oct 28.
2
Exacerbation risk and characterisation of the UK's asthma population from infants to old age.从婴儿到老年,英国哮喘人群的恶化风险及特征。
Thorax. 2018 Apr;73(4):313-320. doi: 10.1136/thoraxjnl-2017-210650. Epub 2017 Oct 26.
3
Trends in international asthma mortality: analysis of data from the WHO Mortality Database from 46 countries (1993-2012).国际哮喘死亡率趋势:对来自 46 个国家(1993-2012 年)的世卫组织死亡率数据库数据的分析。
Lancet. 2017 Sep 2;390(10098):935-945. doi: 10.1016/S0140-6736(17)31448-4. Epub 2017 Aug 7.
4
The impact of comorbidities on productivity loss in asthma patients.合并症对哮喘患者生产力损失的影响。
Respir Res. 2016 Aug 26;17(1):106. doi: 10.1186/s12931-016-0421-9.
5
Patient reported burden of asthma on resource use and productivity across 11 countries in Europe.患者报告的哮喘对欧洲11个国家资源使用和生产力的负担。
Adv Ther. 2015 Apr;32(4):370-80. doi: 10.1007/s12325-015-0204-6. Epub 2015 Apr 26.
6
Predictors of severe exacerbations, poor asthma control, and β-agonist overuse for patients with asthma.哮喘患者严重恶化、哮喘控制不佳和β-激动剂过度使用的预测因素。
J Allergy Clin Immunol Pract. 2014 Nov-Dec;2(6):751-8. doi: 10.1016/j.jaip.2014.06.001. Epub 2014 Jul 25.
7
Asthma control and management in 8,000 European patients: the REcognise Asthma and LInk to Symptoms and Experience (REALISE) survey.8000 例欧洲患者的哮喘控制和管理:识别哮喘并将症状和体验联系起来(REALISE)调查。
NPJ Prim Care Respir Med. 2014 Jun 12;24:14009. doi: 10.1038/npjpcrm.2014.9.
8
Poor Asthma control among US workers: health-related quality of life, work impairment, and health care use.美国工人哮喘控制不佳:与健康相关的生活质量、工作障碍及医疗保健利用情况
J Occup Environ Med. 2014 Apr;56(4):425-30. doi: 10.1097/JOM.0000000000000123.
9
Costs associated with workdays lost and utilization of health care resources because of asthma in daily clinical practice in Spain.在西班牙的日常临床实践中,哮喘导致的工作日损失和医疗资源利用相关成本。
J Investig Allergol Clin Immunol. 2013;23(4):234-41.
10
Occupational exposures and uncontrolled adult-onset asthma in the European Community Respiratory Health Survey II.职业暴露与欧洲社区呼吸健康调查 II 中未控制的成人哮喘。
Eur Respir J. 2014 Feb;43(2):374-86. doi: 10.1183/09031936.00034913. Epub 2013 Aug 15.

评估哮喘的影响:一项针对正在接受治疗的工人的横断面研究。

Assessing the Impact of Asthma: A Cross-Sectional Study in Workers Undergoing Therapy.

作者信息

Omrane Amira, Krayem Latifa, Touil Imen, Romdhani Raja, Brahem Yosra, Boussoffara Leila, Knani Jalel, Khalfallah Taoufik, Boudawara Nadia

机构信息

Department of Occupational Medicine, Teaching Hospital of Taher Sfar Mahdia, Tunisia.

Department of Medicine, Public Hospital Moknine, Monastir, Tunisia.

出版信息

Med Lav. 2025 Apr 17;116(2):15786. doi: 10.23749/mdl.v116i2.15786.

DOI:10.23749/mdl.v116i2.15786
PMID:40243550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12120787/
Abstract

BACKGROUND

This study aimed to investigate the impact of asthma on work productivity among adults receiving asthma therapy.

METHODS

A cross-sectional study involving 101 asthmatic patients treated at the Pulmonology Department of University Hospital in Mahdia (Tunisia) who had been employed for at least six months was conducted over the course of a year. Recruited patients were asked to complete a self-administered questionnaire that consisted of the Simplified Medication Adherence Questionnaire (SMAQ), the Work Productivity and Activity Impairment (WPAI), and the Pichot questionnaire.

RESULTS

The study's participants had a sex ratio of 0.51 and a mean age of 44.1±13.2 years. Exposure to aerocontaminants was high among 64.4% of patients. The majority of the patients were treated with inhaled corticosteroids (ICS) and long-acting beta-agonists (LABA) (54.4%), and nearly half were classified as having moderate asthma. Our findings revealed significant challenges faced by these patients, with 62.4% experiencing poorly controlled or uncontrolled asthma. Additionally, 69.3% were non-adherent to treatment, and 71.3% reported worsening symptoms while at work. They worked an average of 38.3±16.4 hours per week. The impact of general health status on work productivity was measured at 3.3±2.5. Absenteeism and presenteeism rates were 4.2% and 33.1%, respectively, resulting in a productivity loss of 30.4%. Activity impairment was associated with factors such as gender, alcohol consumption, and uncontrolled asthma.

CONCLUSION

Addressing asthma control, working conditions, and mental health emerges as essential strategies to enhance workplace productivity. When evaluating the effectiveness of interventions among active asthmatic patients, presenteeism, absenteeism, and productivity loss should be considered.

摘要

背景

本研究旨在调查哮喘对接受哮喘治疗的成年人工作效率的影响。

方法

一项横断面研究在一年时间内对101名在马赫迪耶(突尼斯)大学医院肺病科接受治疗且已工作至少六个月的哮喘患者进行。招募的患者被要求完成一份自我管理问卷,该问卷包括简化药物依从性问卷(SMAQ)、工作效率和活动受损情况问卷(WPAI)以及皮肖特问卷。

结果

该研究的参与者性别比为0.51,平均年龄为44.1±13.2岁。64.4%的患者暴露于空气污染物中。大多数患者接受吸入性糖皮质激素(ICS)和长效β受体激动剂(LABA)治疗(54.4%),近一半患者被归类为中度哮喘。我们的研究结果揭示了这些患者面临的重大挑战,62.4%的患者哮喘控制不佳或未得到控制。此外,69.3%的患者不坚持治疗,71.3%的患者报告在工作时症状加重。他们平均每周工作38.3±16.4小时。一般健康状况对工作效率的影响评分为3.3±2.5。缺勤率和出勤但工作效率低下率分别为4.2%和33.1%,导致生产力损失30.4%。活动受损与性别、饮酒和未控制的哮喘等因素有关。

结论

解决哮喘控制、工作条件和心理健康问题是提高工作场所生产力的关键策略。在评估对活跃哮喘患者干预措施的有效性时,应考虑出勤但工作效率低下、缺勤和生产力损失情况。