-Regulated Enhances Salt Tolerance in by Modulating Flavonoid Biosynthesis and Reactive Oxygen Species Scavenging.

High-salinity stress induces severe oxidative damage in plants, leading to growth inhibition through cellular redox imbalance. Chalcone synthase (CHS), a pivotal enzyme in the flavonoid biosynthesis pathway, plays critical roles in plant stress adaptation. However, the molecular mechanisms underlying CHS-mediated salt tolerance remain uncharacterized in L., a tropical crop of high economic and ecological significance. Here, we systematically identified the gene family in and revealed tissue-specific and salt-stress-responsive expression patterns, with exhibiting the most pronounced induction under salinity. Transgenic overexpressing displayed enhanced salt tolerance compared to wild-type plants, characterized by elevated activities of antioxidant enzymes: superoxide dismutase (SOD), catalase (CAT), and peroxidase (POD), increased flavonoid accumulation, and reduced reactive oxygen species (ROS) accumulation. Furthermore, we identified the transcription factor as a direct activator of through binding to its promoter. Our findings demonstrate that the regulatory module enhances salt tolerance by orchestrating flavonoid biosynthesis and ROS scavenging. This study provides functional evidence of CHS-mediated salt adaptation in and highlights its potential for improving stress resilience in tropical crops.