INTRODUCTION: Wearable devices that incorporate artificial intelligence (AI) have revolutionised healthcare through continuous monitoring, early detection, and tailored management of chronic diseases. METHODS: This cross-sectional study analysed patients' perceptions, trust, and awareness of AI-driven wearable health technologies, emphasising the identification of primary facilitators and barriers to adoption. A total of 455 participants, comprising individuals with chronic conditions, were recruited through convenience and stratified sampling methods. Data were collected via an online questionnaire that included demographic questions, Likert-scale items, and multiple-choice questions to evaluate awareness of particular AI features and the functionalities of wearable devices. RESULTS AND DISCUSSION: The findings indicated predominantly positive perceptions, with most participants concurring that wearable devices improve proactive care, facilitate remote consultations, and deliver precise health insights. Concerns regarding technical failures, data accuracy, and the potential reduction of human interaction were significant. No notable demographic differences were identified; however, participants with chronic conditions expressed more favourable perceptions. The research emphasises the necessity of user education, technical reliability, and professional oversight for the successful integration of AI-powered wearables in the management of chronic diseases.