Barekar Pooja, Kose Varsha, Dixit Prachi
Department of Obstetrics and Gynecology, NKP Salve Institute of Medical Sciences and Research Centre and Lata Mangeshkar Hospital, Nagpur, IND.
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Nagpur, IND.
Cureus. 2025 Mar 18;17(3):e80759. doi: 10.7759/cureus.80759. eCollection 2025 Mar.
Acute abdominal pain is a common clinical problem in emergency and non-emergency cases. Acute abdomen in systemic lupus erythematosus (SLE) is a challenging diagnostic and therapeutic problem that carries high mortality and morbidity rates. The present study reports a case of a 45-year-old female, a known case of SLE, hypothyroidism, and seizure disorder. The patient presented with chief complaints of pain in the left iliac and lumbar region with a history of amenorrhea for three to four months. Based on the clinical findings, laboratory investigations, and diagnostic assessment involving ultrasonography (USG), the diagnosis of acute abdomen along with tubo-ovarian mass with dermoid cyst and SLE with lupus nephritis and seizure disorder was confirmed. The patient was operated with total abdominal hysterectomy (TAH) with bilateral salpingo-oophorectomy with loop colostomy. The patient was placed in the surgical intensive care unit for observation; however, sepsis developed, and the trauma from the exploratory laparotomy led to septic shock, followed by hypotension and ultimately cardiac arrest. Hence, the cause of death was attributed to sepsis with shock and multiple organ dysfunction syndromes. In conclusion, acute abdomen in SLE suggests that systemic measurement and early laparotomy may improve the prognosis; however, due to chronic inflammatory status and immune-compromised state, the cases should be handled with utmost caution with a multidisciplinary approach due to the increase in the mortality rate.
急性腹痛是急诊和非急诊病例中常见的临床问题。系统性红斑狼疮(SLE)患者的急腹症是一个具有挑战性的诊断和治疗问题,其死亡率和发病率都很高。本研究报告了一例45岁女性病例,该患者已知患有SLE、甲状腺功能减退症和癫痫症。患者主要主诉左髂部和腰部疼痛,并有三到四个月的闭经史。根据临床检查结果、实验室检查以及包括超声检查(USG)在内的诊断评估,确诊为急腹症伴输卵管卵巢肿物合并皮样囊肿,以及SLE伴狼疮性肾炎和癫痫症。患者接受了全腹子宫切除术(TAH)、双侧输卵管卵巢切除术和袢式结肠造口术。患者被安置在外科重症监护病房进行观察;然而,出现了败血症,剖腹探查术造成的创伤导致感染性休克,随后出现低血压,最终心脏骤停。因此,死亡原因归因于败血症伴休克和多器官功能障碍综合征。总之,SLE患者的急腹症表明,全身评估和早期剖腹手术可能会改善预后;然而,由于慢性炎症状态和免疫功能低下状态,鉴于死亡率增加,应采用多学科方法极其谨慎地处理此类病例。