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模仿脊柱关节炎所致指炎的脓肿分枝杆菌手部感染:一例报告

Mycobacterium abscessus Hand Infection Mimicking Dactylitis Due to Spondyloarthritis: A Case Report.

作者信息

Aung Thanda, Celestin Mia

机构信息

Rheumatology, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, USA.

出版信息

Cureus. 2025 Mar 17;17(3):e80740. doi: 10.7759/cureus.80740. eCollection 2025 Mar.

DOI:10.7759/cureus.80740
PMID:40248562
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12003702/
Abstract

is an environmental, rapid-growing non-tuberculosis commonly found in soil and water. While typically causing pulmonary infections, it can present with musculoskeletal manifestations that mimic inflammatory arthritis. We present a case of a 73-year-old woman who developed progressive hand tenosynovitis following a gardening injury. The clinical presentation initially suggested seronegative spondyloarthritis, particularly due to the presence of dactylitis. However, synovial biopsy and culture ultimately revealed subsp. infection. This case highlights the importance of considering atypical infections in the differential diagnosis of apparent inflammatory arthritis, especially with unilateral involvement and inadequate response to conventional therapy.

摘要

是一种环境中常见的快速生长的非结核分枝杆菌,通常存在于土壤和水中。虽然它通常引起肺部感染,但也可出现类似炎性关节炎的肌肉骨骼表现。我们报告一例73岁女性,在园艺受伤后发生进行性手部腱鞘炎。临床表现最初提示血清阴性脊柱关节炎,特别是由于存在指(趾)炎。然而,滑膜活检和培养最终显示为亚种感染。该病例强调了在明显炎性关节炎的鉴别诊断中考虑非典型感染的重要性,尤其是单侧受累且对传统治疗反应不佳时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/12003702/39fcf1992b25/cureus-0017-00000080740-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/12003702/f9b40a30b007/cureus-0017-00000080740-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/12003702/837f084970b2/cureus-0017-00000080740-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/12003702/39fcf1992b25/cureus-0017-00000080740-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/12003702/f9b40a30b007/cureus-0017-00000080740-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/12003702/837f084970b2/cureus-0017-00000080740-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/12003702/39fcf1992b25/cureus-0017-00000080740-i03.jpg

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本文引用的文献

1
Disseminated Mycobacterium abscessus infection with osteoarticular manifestations as an important differential diagnosis of inflammatory arthritis: A case report and literature review.播散性脓肿分枝杆菌感染伴骨关节炎表现,作为炎症性关节炎的重要鉴别诊断:病例报告及文献复习。
Mod Rheumatol Case Rep. 2023 Dec 29;8(1):49-54. doi: 10.1093/mrcr/rxad054.
2
Complex Infections: A Retrospective Cohort Study.复杂感染:一项回顾性队列研究
Open Forum Infect Dis. 2018 Feb 9;5(2):ofy022. doi: 10.1093/ofid/ofy022. eCollection 2018 Feb.
3
Mycobacterium abscessus Displays Fitness for Fomite Transmission.
脓肿分枝杆菌表现出通过污染物传播的适应性。
Appl Environ Microbiol. 2017 Sep 15;83(19). doi: 10.1128/AEM.00562-17. Print 2017 Oct 1.
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Treatment of Mycobacterium abscessus Infection.脓肿分枝杆菌感染的治疗
Emerg Infect Dis. 2016 Mar;22(3):511-4. doi: 10.3201/eid2203.150828.
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Mycobacterium abscessus Complex Infections in Humans.人类脓肿分枝杆菌复合群感染
Emerg Infect Dis. 2015 Sep;21(9):1638-46. doi: 10.3201/2109.141634.
6
Clinical and radiological presentations of late-onset spondyloarthritis.迟发性脊柱关节炎的临床和影像学表现。
ISRN Rheumatol. 2011;2011:840475. doi: 10.5402/2011/840475. Epub 2011 Mar 20.
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Clinical and pathological characteristics of mycobacterial tenosynovitis and arthritis.分枝杆菌腱鞘炎和关节炎的临床和病理特征。
Infection. 2013 Apr;41(2):457-64. doi: 10.1007/s15010-013-0403-5. Epub 2013 Jan 19.
8
Treatment of the wrist in rheumatoid arthritis.类风湿关节炎手腕部的治疗
J Hand Surg Am. 2008 Jan;33(1):113-23. doi: 10.1016/j.jhsa.2007.09.011.
9
Mycobacterium abscessus: an emerging rapid-growing potential pathogen.脓肿分枝杆菌:一种新出现的快速生长的潜在病原体。
APMIS. 2006 May;114(5):319-28. doi: 10.1111/j.1600-0463.2006.apm_390.x.