Yildiz Eda, Zaffar Duha, Ozturk N Begum, Gurakar Merve, Donmez A Eylul, Toruner Merih Deniz, Simsek Cem, Gurakar Ahmet
Department of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Department of Internal Medicine, University of Maryland Midtown Campus, Baltimore, Maryland, USA.
Hepatol Forum. 2025 Mar 1;6(2):77-86. doi: 10.14744/hf.2024.2024.0057. eCollection 2025.
Alcoholic liver disease(ALD) is considered as a growing public health issue with universally increasing disease burden. Various genetic and environmental factors play role in its etiology. ALD recently has become the major indication for Liver Transplantation (LT). Most LT programs select their candidates by adhering to six months of alcohol abstinence policy. Nevertheless, early liver transplantation (ELT) has become a subject of research, both in Europe and the United States, as an effective and lifesaving option among highly selected severe alcohol-associated hepatitis (SAH) patients. ELT is a promising way in the management of ALD, perhaps changing clinical practice for carefully selected patient groups.
酒精性肝病（ALD）被认为是一个日益严重的公共卫生问题，疾病负担普遍增加。各种遗传和环境因素在其病因中起作用。ALD最近已成为肝移植（LT）的主要指征。大多数LT项目通过坚持六个月戒酒政策来选择候选人。然而，早期肝移植（ELT）在欧洲和美国都已成为研究课题，作为高度选择的严重酒精性肝炎（SAH）患者的一种有效且挽救生命的选择。ELT是管理ALD的一种有前景的方法，可能会改变精心挑选患者群体的临床实践。
