Al Sakka Amini Ruaa, Hakmi Abdulhafiz, Hendi Hamza, Abo Saada Sawsan, Etr Aladdin
Abdali hospital, Amman, Jordan.
Ain Shams University, Cairo, Egypt.
Int J Surg Case Rep. 2025 May;130:111297. doi: 10.1016/j.ijscr.2025.111297. Epub 2025 Apr 18.
Giant congenital melanocytic nevi (GCMN) are rare, large pigmented lesions present at birth that can significantly impact a patient's physical appearance and psychological well-being.
This case report presents a successful outcome of serial surgical excision for a GCMN in a 10-year-old Syrian male. The patient presented with a large GCMN covering his entire nose and part of his left infraorbital region, causing significant psychological distress. Despite no immediate symptoms, a staged approach using serial surgical excisions and skin grafting was applied, resulting in the complete removal of the GCMN over 18 months. The patient experienced no significant complications and achieved a successful aesthetic result, allowing him to return to school and resume normal activities.
The best treatment for congenital melanocytic nevi (CMN) is uncertain and varies based on the nevus characteristics. However, early excision of large nevi can reduce melanoma risk and relieve psychological distress for both the child and parents.
Congenital melanocytic nevi (CMN) are rare benign lesions that can potentially become malignant, affecting patients' well-being. This case highlights the effectiveness of serial surgical excision in managing GCMN, demonstrating the potential for successful outcomes even in complex cases.
巨大先天性黑素细胞痣(GCMN)是出生时就存在的罕见、巨大色素沉着病变,会对患者的外貌和心理健康产生重大影响。
本病例报告展示了一名10岁叙利亚男性患者的巨大先天性黑素细胞痣经系列手术切除取得成功的结果。该患者出现一个巨大先天性黑素细胞痣,覆盖其整个鼻子和部分左眶下区域,造成严重的心理困扰。尽管当时没有直接症状,但采用了系列手术切除和皮肤移植的分期方法,在18个月内成功完全切除了巨大先天性黑素细胞痣。患者未出现重大并发症,取得了成功的美学效果,使其能够重返学校并恢复正常活动。
先天性黑素细胞痣(CMN)的最佳治疗方法尚不确定,且因痣的特征而异。然而,早期切除大的痣可降低黑色素瘤风险,并减轻患儿及其父母的心理困扰。
先天性黑素细胞痣(CMN)是罕见的良性病变,有可能恶变,影响患者的健康。本病例突出了系列手术切除在处理巨大先天性黑素细胞痣方面的有效性,表明即使在复杂病例中也有取得成功结果的潜力。