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男性乳腺腺样囊性癌:一例报告及文献复习

Adenoid cystic carcinoma in a male breast: a case report and literature review.

作者信息

Kapoor Vatsala, Moses Cara, Hanna Sarah P, Odom John W

机构信息

Medical College of Georgia, 1120 5th St, Augusta, GA 30912, United States.

Department of Surgery, St. Josephs/Candler Health System, 11704 Mercy Boulevard, Savannah, GA 31419, United States.

出版信息

J Surg Case Rep. 2025 Apr 19;2025(4):rjaf226. doi: 10.1093/jscr/rjaf226. eCollection 2025 Apr.

DOI:10.1093/jscr/rjaf226
PMID:40255333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12008116/
Abstract

Breast adenoid cystic carcinoma (BACC) is a rare occurrence constituting less than 0.1% of primary breast cancers. BACC is even more rare in male patients. Furthermore, there are currently no concrete treatment guidelines for BACC. Therefore, it is imperative to conduct a thoughtful evaluation and diagnostic workup when a potential case is encountered. We report a 63-year old male who initially presented to the dermatologist with a nonhealing inflamed leiomyoma of the left breast, raising suspicion for inflammatory breast cancer. A percutaneous biopsy was performed, and pathology revealed fragments of cribriform and papillary-like carcinoma, leading to a differential diagnosis including adenoid cystic carcinoma and basal-like ductal carcinoma . A modified radical mastectomy was performed, and final surgical pathology revealed BACC. The patient did not receive any adjuvant therapy and is currently without any evidence of disease.

摘要

乳腺腺样囊性癌(BACC)是一种罕见疾病,在原发性乳腺癌中占比不到0.1%。BACC在男性患者中更为罕见。此外,目前尚无针对BACC的具体治疗指南。因此,当遇到疑似病例时,必须进行全面的评估和诊断检查。我们报告一例63岁男性患者,最初因左侧乳腺炎性平滑肌瘤不愈合就诊于皮肤科医生,引发了炎性乳腺癌的怀疑。进行了经皮活检,病理显示筛状和乳头状癌碎片,鉴别诊断包括腺样囊性癌和基底样导管癌。实施了改良根治性乳房切除术,最终手术病理显示为BACC。该患者未接受任何辅助治疗,目前无疾病证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1249/12008116/1082691c315c/rjaf226f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1249/12008116/7be0207b57cd/rjaf226f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1249/12008116/dc2baa272826/rjaf226f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1249/12008116/26695f499baf/rjaf226f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1249/12008116/1082691c315c/rjaf226f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1249/12008116/7be0207b57cd/rjaf226f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1249/12008116/dc2baa272826/rjaf226f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1249/12008116/26695f499baf/rjaf226f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1249/12008116/1082691c315c/rjaf226f4.jpg

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本文引用的文献

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Adenoid Cystic Carcinoma of the Breast: Multimodality Imaging Findings and Review of the Literature.乳腺腺样囊性癌:多模态影像学表现及文献复习。
Acad Radiol. 2023 Jun;30(6):1107-1117. doi: 10.1016/j.acra.2022.10.003. Epub 2022 Nov 7.
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Adenoid Cystic Carcinoma of the Breast in a Male Patient: A Case Report and Literature Review.男性患者乳腺腺样囊性癌:一例报告及文献复习
Front Oncol. 2022 Jul 7;12:905997. doi: 10.3389/fonc.2022.905997. eCollection 2022.
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Breast adenoid cystic carcinoma: a report of seven cases and literature review.
乳腺腺样囊性癌:7 例报告及文献复习。
BMC Surg. 2022 Mar 24;22(1):113. doi: 10.1186/s12893-022-01560-9.
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Predictors of Outcome in Mammary Adenoid Cystic Carcinoma: A Multi-Institutional Study.乳腺腺样囊性癌预后的预测因素:一项多机构研究。
Am J Surg Pathol. 2020 Feb;44(2):214-223. doi: 10.1097/PAS.0000000000001378.
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Adenoid cystic carcinoma of breast: Recent advances.乳腺腺样囊性癌:最新进展
World J Clin Cases. 2014 Dec 16;2(12):732-41. doi: 10.12998/wjcc.v2.i12.732.
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A comparison of the demographics, clinical features, and survival of patients with adenoid cystic carcinoma of major and minor salivary glands versus less common sites within the Surveillance, Epidemiology, and End Results registry.比较主要和次要涎腺与《监测、流行病学和最终结果》登记处内较少见部位的腺样囊性癌患者的人口统计学、临床特征和生存情况。
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Clinical review--breast adenoid cystic carcinoma.临床综述——乳腺腺样囊性癌。
Breast. 2012 Apr;21(2):124-7. doi: 10.1016/j.breast.2011.11.006. Epub 2011 Dec 10.
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Adenoid cystic carcinoma of the breast in the United States (1977 to 2006): a population-based cohort study.美国乳腺腺样囊性癌(1977 年至 2006 年):一项基于人群的队列研究。
Breast Cancer Res. 2010;12(4):R54. doi: 10.1186/bcr2613. Epub 2010 Jul 23.
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Triple-negative breast cancer: clinical features and patterns of recurrence.三阴性乳腺癌:临床特征与复发模式
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Basal phenotype of ductal carcinoma in situ: recognition and immunohistologic profile.导管原位癌的基底样表型:识别与免疫组织学特征
Mod Pathol. 2006 Nov;19(11):1506-11. doi: 10.1038/modpathol.3800678. Epub 2006 Aug 25.