Tran Vivie, Mai Megan T, Kodam Sai, Brandi Luis, Jaggernauth Simeon
Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA.
Medical School, Texas Tech University Health Sciences Center, Lubbock, USA.
Cureus. 2025 Mar 19;17(3):e80857. doi: 10.7759/cureus.80857. eCollection 2025 Mar.
This case report presents a 72-year-old male with a history of diffuse large B-cell lymphoma (DLBCL) who was found to have a 2.6 cm left renal mass during surveillance imaging. The clinical challenge lay in distinguishing between a recurrence of DLBCL and a new primary renal cell carcinoma (RCC), as both diseases are treated with different paradigms. A biopsy confirmed clear cell RCC, and the patient underwent a left nephrectomy with no evidence of metastasis or recurrence of lymphoma. This case highlights the importance of a biopsy in clarifying the diagnosis of renal masses, particularly in patients with prior malignancies. It also explores the potential role of radiation therapy as an alternative treatment option in cases where surgery may pose significant risks. A more comprehensive multidisciplinary approach would optimize patient outcomes and ensure individualized care.
本病例报告介绍了一名72岁男性，有弥漫性大B细胞淋巴瘤（DLBCL）病史，在监测成像中发现左肾有一个2.6厘米的肿块。临床面临的挑战在于区分DLBCL复发和新发原发性肾细胞癌（RCC），因为这两种疾病的治疗模式不同。活检证实为透明细胞RCC，患者接受了左肾切除术，未发现淋巴瘤转移或复发迹象。本病例强调了活检在明确肾肿块诊断中的重要性，特别是对于有既往恶性肿瘤病史的患者。它还探讨了放射治疗在手术可能带来重大风险的情况下作为替代治疗选择的潜在作用。更全面的多学科方法将优化患者预后并确保个性化护理。
