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一名61岁黄疸和胆石症合并自身免疫性肝炎女性的病例报告

A Case Report of a 61-Year-Old Woman With Jaundice and Cholelithiasis Presenting With Autoimmune Hepatitis.

作者信息

Michalakis Nicholas P, Patel Archit, Awais Muhammad

机构信息

Internal Medicine, Piedmont Macon Medical Center, Macon, USA.

Graduate Medical Education, Piedmont Macon Medical Center, Macon, USA.

出版信息

Cureus. 2025 Mar 19;17(3):e80829. doi: 10.7759/cureus.80829. eCollection 2025 Mar.

Abstract

Autoimmune hepatitis (AIH) is a complex disease with a chronic cell-mediated immunologic process against healthy liver cells. The clinical presentation can vary since the exact cause of AIH is multifactorial. Here, we report a case of a 61-year-old woman with a past medical history of post-traumatic stress disorder and hypothyroidism who presented clinically with diffuse abdominal distention, nausea, vomiting, jaundice, rash on the torso and legs, and tea-burnt orange urine. The patient underwent an initial workup with a complete blood count (CBC), comprehensive metabolic panel (CMP), and gamma-glutamyl transpeptidase (GGT), with results leading towards a mixed intra- and extrahepatic process. This report will show various findings related to AIH to improve the detection and treatment of these patients early on.

摘要

自身免疫性肝炎(AIH)是一种复杂的疾病,其特征是针对健康肝细胞的慢性细胞介导免疫过程。由于AIH的确切病因是多因素的,其临床表现可能各不相同。在此,我们报告一例61岁女性病例,该患者有创伤后应激障碍和甲状腺功能减退的既往病史,临床症状为弥漫性腹胀、恶心、呕吐、黄疸、躯干和腿部皮疹以及浓茶色尿液。患者接受了包括全血细胞计数(CBC)、综合代谢指标(CMP)和γ-谷氨酰转肽酶(GGT)在内的初步检查,结果提示存在肝内和肝外混合性病变。本报告将展示与AIH相关的各种发现,以尽早改善对这些患者的检测和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7560/12007933/5c652b7c00e4/cureus-0017-00000080829-i01.jpg

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