Mandelia Ankur, Gupta Arun Kumar, Verma Devendra Kumar, Sharma Sanjeev
Senior Resident, Department of Paediatric Surgery, All India Institute of Medical Sciences , New Delhi 110029, India .
J Clin Diagn Res. 2013 Sep;7(9):1941-5. doi: 10.7860/JCDR/2013/6158.3365. Epub 2013 Sep 10.
Magnetic Resonance Cholangio-Pancreatography (MRCP) is a non-invasive radiological investigation which can be performed rapidly and which does not expose the patients to ionised radiations or iodinated contrast material. The present study was conducted to evaluate the role of MRCP in detection of Common Bile Duct (CBD) stones in patients with suspected choledocholithiasis.
This prospective study included 30 patients with a suspicion of choledocholithiasis which was based on clinical evaluation, biochemical or radiological investigations. Ultrasonography and MRCP were performed in all patients. All patients underwent open surgery. CBD exploration was performed in all patients, either due to presence of palpable stones or due to the presence of dilated CBD (> 7 mm). Demonstration of CBD stones intra-operatively was considered the 'gold standard' for their presence, defined as stones visualised and extracted or attempted for extraction during surgical CBD exploration.
Intra-operatively, 21 (70%) out of 30 patients had cholelithiasis. 26 (86.67%) out of 30 patients had dilated CBD stones intra-operatively. In 20 (66.67%) out of 30 patients, choledocholithiasis was detected intra-operatively. The sensitivity, specificity, positive and negative predictive value of ultrasonography in detecting CBD stones in the present study was 65%, 60%, 76.47% and 46.15% respectively. The sensitivity, specificity, positive and negative predictive value of MRCP in diagnosis of CBD stones in the present study was 95%, 90%, 95% and 90% respectively.
MRCP is a non-invasive investigation without complications and it has high sensitivity, specificity and positive and negative predictive values in detection of CBD stones. MRCP should be done in all cases with a suspicion of CBD stones, where facilities and expertise are available.
磁共振胰胆管造影(MRCP)是一种非侵入性的放射学检查方法,能够快速完成,且不会使患者暴露于电离辐射或含碘造影剂中。本研究旨在评估MRCP在疑似胆总管结石患者中检测胆总管(CBD)结石的作用。
这项前瞻性研究纳入了30例基于临床评估、生化或放射学检查怀疑患有胆总管结石的患者。所有患者均接受了超声检查和MRCP检查。所有患者均接受了开放手术。所有患者均因可触及结石或胆总管扩张(>7mm)而进行了胆总管探查。术中证实胆总管结石的存在被视为其存在的“金标准”,定义为在手术胆总管探查期间可视化并取出或尝试取出的结石。
术中,30例患者中有21例(70%)患有胆石症。30例患者中有26例(86.67%)术中发现胆总管扩张并有结石。30例患者中有20例(66.67%)术中检测出胆总管结石。在本研究中,超声检测胆总管结石的敏感性、特异性、阳性预测值和阴性预测值分别为65%、60%、76.47%和46.15%。本研究中,MRCP诊断胆总管结石的敏感性、特异性、阳性预测值和阴性预测值分别为95%、90%、95%和90%。
MRCP是一种无并发症的非侵入性检查,在检测胆总管结石方面具有高敏感性、特异性以及阳性和阴性预测值。在有条件和专业技术的情况下,所有疑似胆总管结石的病例均应进行MRCP检查。