Xiao Zhiying, Bai Hui, Zhang Yumeng
Department of Urology, The Second Hospital of Shandong University, Jinan, China.
Department of Medical Radiology, The Second Hospital of Shandong University, Jinan, China.
Curr Urol. 2024 Dec;18(4):291-294. doi: 10.1097/CU9.0000000000000236. Epub 2024 Jan 10.
The aim of this study was to develop and evaluate two deep-learning (DL) models for predicting spontaneous ureteral stone passage (SSP).
A total of 1217 patients with thin-layer computed tomography-confirmed ureteral stones in our hospital from January 2019 to December 2022 were retrospectively examined. These patients were grouped into 3 data sets: the training set (n = 1000), the validation set ( = 100), and the test set ( = 117). Two DL models based on residual neural network (ResNet)-2-dimensional (2D) ResNet29 and 3-dimensional (3D) ResNet29-were separately developed, trained, and assessed. The predictive ability of a conventional approach using a stone diameter of <5 mm on computed tomography was investigated, and the results were compared with those of the two DL models.
Of the 1217 patients, SSP was reported in 446 (36.6%). The total accuracy, sensitivity, and specificity were 76.9%, 56.1%, and 90.8% for the stone diameter approach; 87.1%, 84.2%, and 92.7% for the 2D ResNet29 model; and 90.6%, 88.2%, and 95.1% for the 3D ResNet29 model, respectively. Both the 2D and 3D ResNet29 models showed significantly higher accuracy than the stone diameter approach. Receiver operating characteristic curve analysis showed that both DL models had a significantly higher area under the curve than the stone diameter-based classification.
The DL models, particularly the 3D model, are novel and effective methods for predicting SSP rates. Using such models may help determine whether a patient should receive surgical intervention or expect a long interval before stone passage.
本研究旨在开发和评估两种用于预测输尿管结石自然排出(SSP)的深度学习(DL)模型。
回顾性研究了2019年1月至2022年12月我院1217例经薄层计算机断层扫描确诊为输尿管结石的患者。这些患者被分为3个数据集:训练集(n = 1000)、验证集(n = 100)和测试集(n = 117)。分别开发、训练和评估了基于残差神经网络(ResNet)的两种DL模型——二维(2D)ResNet29和三维(3D)ResNet29。研究了使用计算机断层扫描上结石直径<5 mm的传统方法的预测能力,并将结果与两种DL模型的结果进行比较。
在1217例患者中,446例(36.6%)报告有输尿管结石自然排出。结石直径法的总准确率、敏感性和特异性分别为76.9%、56.1%和90.8%;2D ResNet29模型分别为87.1%、84.2%和92.7%;3D ResNet29模型分别为90.6%、88.2%和95.1%。2D和3D ResNet29模型的准确率均显著高于结石直径法。受试者工作特征曲线分析表明,两种DL模型的曲线下面积均显著高于基于结石直径的分类。
DL模型,尤其是3D模型,是预测输尿管结石自然排出率的新颖且有效的方法。使用此类模型可能有助于确定患者是否应接受手术干预或预计结石排出前的间隔时间较长。