May H, Gries G
MMW Munch Med Wochenschr. 1977 Feb 4;119(5):155-8.
Inflammatory diseases of the colon can be differentiated by means of their chymotrypsin A excretion in the stool. In proctosigmoiditis and a group of comparable gastroenterological cases, the mean excretion level is between 170 and 200 mug per gram of stool. The chymotrypsin A level in proctocolitis, on the other hand, is significantly higher in all stages and increases with increasing activity of the disease. This brings a further diagnostic criterion to the clinical and endoscopic differences between proctosigmoiditis and proctocolitis (colitis ulcerosa). The fundamentally different behavior in the excretion of chymotrypsin A in the stool supports the hypothesis of two diseases differing from each other.
结肠炎症性疾病可通过粪便中糜蛋白酶A的排泄情况进行区分。在直肠乙状结肠炎以及一组类似的胃肠病病例中，每克粪便中糜蛋白酶A的平均排泄水平在170至200微克之间。另一方面，在全结肠炎的各个阶段，糜蛋白酶A水平均显著更高，且随着疾病活动度的增加而升高。这为直肠乙状结肠炎和全结肠炎（溃疡性结肠炎）之间的临床及内镜差异带来了另一项诊断标准。粪便中糜蛋白酶A排泄情况的根本不同表现支持了两种彼此不同疾病的假说。
