Födisch H J, Toledo R
Klin Padiatr. 1978 Mar;190(2):190-5.
Crohn's Disease and Ulcerative Colitis play a vital role in the differential diagnosis of inflammatory diseases of the colon during childhood. Pediatricians, radiologists, pediatric surgions and pediatric pathologists have been frequently confronted with the problem of distinguishing the two diseases. Morphologically, both diseases could be definitely differentiated but this is largely dependent on the art and the quantity of the submitted materials to be examined. It is, therefor, important to consider and differentiate their macroscopic and histologic features in relation to the type of inflammation, the pattern of its localization and spread, the involvement of different layers of the large intestinal wall etc. The basic essential differences lie on the primary site of injury and the pattern of its inflammatory response. Both specific and non-specific characteristics of the two diseases would be discussed here.
克罗恩病和溃疡性结肠炎在儿童期结肠炎症性疾病的鉴别诊断中起着至关重要的作用。儿科医生、放射科医生、小儿外科医生和儿科病理学家经常面临区分这两种疾病的问题。从形态学上看，这两种疾病可以明确区分，但这在很大程度上取决于送检材料的技术和数量。因此，重要的是要根据炎症类型、炎症定位和扩散模式、大肠壁不同层次的受累情况等来考虑和区分它们的宏观和组织学特征。两者的基本本质区别在于损伤的原发部位及其炎症反应模式。这里将讨论这两种疾病的特异性和非特异性特征。
