Whitlock Faith, Al-Makki Akram, Shepler Brian
Purdue University College of Pharmacy, West Lafayette, USA.
IU Health Arnett Nephrology, Lafayette, USA.
J Med Case Rep. 2025 Apr 21;19(1):183. doi: 10.1186/s13256-025-05217-y.
This case report presents the first documented instance of vaginal candidiasis linked to the intake of a hair, skin, and nails supplement.
A 64-year-old Caucasian female patient, with a history of chronic kidney disease and multiple comorbidities, developed symptoms of vaginal yeast infection after beginning the supplement. The adverse event was evaluated using the Naranjo Adverse Drug Reaction Probability Scale, scoring a 5, indicating a probable association. Despite extensive literature searches, no similar cases were found, suggesting this might be a unique reaction. This report highlights potential safety concerns with dietary supplements, particularly those not regulated by the Food and Drug Administration, underscoring the need for further investigation into their adverse effects.
The case emphasizes the importance of considering dietary supplements as potential contributors to adverse health events, especially in patients with complex medical histories.
本病例报告呈现了首例有记录的与摄入毛发、皮肤和指甲补充剂相关的阴道念珠菌病病例。
一名64岁的白种女性患者，有慢性肾病病史且患有多种合并症，在开始服用该补充剂后出现了阴道酵母菌感染症状。使用纳伦霍药物不良反应概率量表对该不良事件进行评估，得分为5分，表明可能存在关联。尽管进行了广泛的文献检索，但未发现类似病例，这表明这可能是一种独特的反应。本报告强调了膳食补充剂潜在的安全问题，尤其是那些不受美国食品药品监督管理局监管的产品，凸显了对其不良反应进行进一步调查的必要性。
该病例强调了将膳食补充剂视为不良健康事件潜在因素的重要性，尤其是对于有复杂病史的患者。
