Zhang Kai, Teng Zeng, Li Ailing, Zhang Nan, Wang Ruixue, Wei Shuimiao, Ni Cuiping
School of Nursing, China Medical University, Shenyang, Liaoning, China.
Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Front Med (Lausanne). 2025 Apr 7;12:1530465. doi: 10.3389/fmed.2025.1530465. eCollection 2025.
About 89% of global End-stage renal disease (ESRD) patients receive hemodialysis. Data show that about 40% ~ 60% of dialysis patients are young and middle-aged. Hemodialysis significantly impacts the daily life and rehabilitation of patients, underscoring the urgency of understanding their experiences and needs. However, findings from previous individual qualitative studies may lack representativeness.
This study used Meta-synthesis to offer a thorough understanding of the lived experiences, psychological states, and needs of young and middle-aged hemodialysis patients.
Systematic review and meta-synthesis.
A systematic search was conducted in PubMed, Embase, The Cochrane Library, Web of Science, CINAHL, CBM, CNKI, WanFang, and VIP databases from the establishment of each database to November 4, 2024, targeting qualitative studies on the experiences of young and middle-aged hemodialysis patients (aged 18-65 years old). Quality assessment used the Joanna Briggs Institute's 2016 Checklist for Qualitative Research, followed by meta-synthesis. The study's reporting was informed by the principles of the Enhancing Transparency in Reporting the Synthesis of Qualitative Research (ENTREQ) framework. The thematic analysis approach was employed to synthesize the findings.
Twenty-two studies were included, covering 14 countries. The inclusion of 22 studies yielded 83 findings, categorized into nine subthemes and condensed into four overarching themes: negative emotional experiences toward illness and hemodialysis, experience of financial problems due to long-term hemodialysis treatment, disruptions to normal life, and seeking multiple forms of support among hemodialysis patients.
Healthcare providers should attach importance to this group, to meet their specific needs, and support their active recovery. The goal is to help them relieve negative emotions, reduce financial burden, return to normal life and meet multiple forms of support.
全球约89%的终末期肾病（ESRD）患者接受血液透析治疗。数据显示，约40%至60%的透析患者为中青年。血液透析对患者的日常生活和康复有重大影响，凸显了了解他们的经历和需求的紧迫性。然而，以往个体质性研究的结果可能缺乏代表性。
本研究采用元整合方法，深入了解中青年血液透析患者的生活经历、心理状态和需求。
系统评价与元整合。
从各数据库建立至2024年11月4日，在PubMed、Embase、Cochrane图书馆、Web of Science、CINAHL、CBM、CNKI、万方和维普数据库中进行系统检索，检索针对中青年血液透析患者（年龄18至65岁）经历的质性研究。质量评估采用乔安娜·布里格斯研究所2016年质性研究核对清单，随后进行元整合。本研究的报告遵循了提高质性研究综合报告透明度（ENTREQ）框架的原则。采用主题分析法对研究结果进行整合。
纳入22项研究，涵盖14个国家。这22项研究共产生83项结果，分为9个子主题，并浓缩为4个总体主题：对疾病和血液透析的负面情绪体验、长期血液透析治疗导致的经济问题体验、正常生活受到干扰以及血液透析患者寻求多种形式的支持。
医疗服务提供者应重视这一群体，满足他们的特殊需求，支持他们积极康复。目标是帮助他们缓解负面情绪，减轻经济负担，回归正常生活，并获得多种形式的支持。
