Niazi Fayez Hussain, AlTowayan Sarah AbdulRahman, Arjumand Bilal, Alkhuwaiter Shahad Suliman, Aljuailan Roqayah Ibrahim, Albahoth Ahmad Sulaiman, Ahmed Syed Zubairuddin, Elsayed Hend Mohamed, Luddin Norhayati
Department of Restorative and Prosthetic Dental Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, Saudi Arabia.
Department of Conservative Dental Sciences, College of Dentistry, Qassim University, Buraidah, Saudi Arabia.
Microsc Res Tech. 2025 Sep;88(9):2560-2568. doi: 10.1002/jemt.24875. Epub 2025 Apr 22.
Remineralizing fillers Amorphous-calcium-phosphate nanoparticles (ACP-NPs), hydroxyapatite (HA-NPs), and cerium dioxide (CeONPs) on the micro-tensile bond strength (μTBS) and degree of conversion (DC) of the experimental adhesive (EA) to caries-affected dentin (CAD). Forty molars with carious lesions on the occlusal surface extending to the middle third of the dentin were included. The characterization of ACP-NPs, HA-NPs, and CeO-NPs was performed using SEM and EDX. CAD samples were arbitrarily assigned to four groups based on the application of remineralizing fillers infused into EA. Group 1, Unmodified EA; Group 2, 5% ACP-NPs in EA; Group 3, 5% HA-NPs in EA; and Group 4, 5% CeO-NPs in EA. The composite buildup on the CAD surface was followed by artificial aging. μTBS measurements were evaluated using UTM. The DC of the modified EA was assessed using FTIR spectroscopy. One-way ANOVA and Tukey post hoc tests were used to analyze μTBS and DC. CeO-NPs + EA displayed the highest bond integrity scores. The unmodified EA samples exhibited the lowest μTBS values. ACP-NPs + EA and the unmodified adhesive demonstrated comparable bond strength (p > 0.05). DC of samples in Group 2: ACP-NPs + EA (66.11 ± 6.33) was comparable to Group 1 HA-NPs (73.51 ± 4.37) (p > 0.05). The highest DC was observed in Group 1 (Unmodified EA). CeO-NPs have the potential to improve bond strength scores when used as a remineralizing filler in EA adhesives. However, the incorporation of NPs at 5% in adhesive reduced the DC.
再矿化填料 无定形磷酸钙纳米颗粒（ACP-NPs）、羟基磷灰石（HA-NPs）和二氧化铈（CeONPs）对实验性粘合剂（EA）与龋损牙本质（CAD）的微拉伸粘结强度（μTBS）和转化率（DC）的影响。纳入40颗咬合面龋损延伸至牙本质中三分之一的磨牙。使用扫描电子显微镜（SEM）和能量散射X射线光谱仪（EDX）对ACP-NPs、HA-NPs和CeO-NPs进行表征。根据注入EA中的再矿化填料的应用情况，将CAD样本随机分为四组。第1组，未改性EA；第2组，EA中含5% ACP-NPs；第3组，EA中含5% HA-NPs；第4组，EA中含5% CeO-NPs。在CAD表面进行复合树脂堆积后进行人工老化。使用万能材料试验机（UTM）评估μTBS测量值。使用傅里叶变换红外光谱仪（FTIR）评估改性EA的DC。采用单因素方差分析和Tukey事后检验分析μTBS和DC。CeO-NPs + EA显示出最高的粘结完整性评分。未改性EA样本的μTBS值最低。ACP-NPs + EA与未改性粘合剂表现出相当的粘结强度（p > 0.05）。第2组样本的DC：ACP-NPs + EA（66.11 ± 6.33）与第1组HA-NPs（73.51 ± 4.37）相当（p > 0.05）。在第1组（未改性EA）中观察到最高的DC。当CeO-NPs用作EA粘合剂中的再矿化填料时，有提高粘结强度评分的潜力。然而，在粘合剂中加入5%的纳米颗粒会降低DC。
