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北领地年轻原住民患者慢性肾病进展迅速。

Rapid chronic kidney disease progression in younger, First Nations patients in the Northern Territory.

作者信息

Chen Winnie, Adegboye Oyelola, Gorham Gillian, Abeyaratne Asanga, Majoni Sandawana William, Taylor Sean, Heard Samuel, Munasinghe Harshana, Hare Matthew J L, Cass Alan

机构信息

Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.

Department of Nephrology, Royal Darwin Hospital, NT Health, Darwin, Northern Territory, Australia.

出版信息

Intern Med J. 2025 May;55(5):860-863. doi: 10.1111/imj.70062. Epub 2025 Apr 22.

DOI:10.1111/imj.70062
PMID:40260896
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12077581/
Abstract

This 6-year retrospective cohort study investigated the progression of chronic kidney disease (CKD) among Australian First Nations patients in remote Northern Territory. We found that younger patients (age less than 50 years) were at a higher risk of progression to kidney replacement therapy or death compared to older adults. The results indicate a need to target early CKD intervention efforts to younger patients at risk of rapid progression.

摘要

这项为期6年的回顾性队列研究调查了澳大利亚北领地偏远地区原住民患者慢性肾脏病（CKD）的进展情况。我们发现，与老年人相比，年轻患者（年龄小于50岁）进展至肾脏替代治疗或死亡的风险更高。结果表明，有必要针对有快速进展风险的年轻患者开展早期CKD干预工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0f7/12077581/523fdfb8e3fa/IMJ-55-860-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0f7/12077581/39a552e68806/IMJ-55-860-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0f7/12077581/523fdfb8e3fa/IMJ-55-860-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0f7/12077581/39a552e68806/IMJ-55-860-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0f7/12077581/523fdfb8e3fa/IMJ-55-860-g002.jpg

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本文引用的文献

1
Costs and healthcare use of patients with chronic kidney disease in the Northern Territory, Australia.澳大利亚北领地慢性肾脏病患者的成本和医疗保健利用情况。
BMC Health Serv Res. 2024 Jul 9;24(1):791. doi: 10.1186/s12913-024-11258-8.
2
Developing an integrated clinical decision support system for the early identification and management of kidney disease-building cross-sectoral partnerships.开发一个综合临床决策支持系统，用于早期识别和管理肾脏疾病——建立跨部门合作关系。
BMC Med Inform Decis Mak. 2024 Mar 8;24(1):69. doi: 10.1186/s12911-024-02471-w.
3
Recommendations for culturally safe clinical kidney care for First Nations Australians: a guideline summary.
推荐为澳大利亚原住民提供文化安全的临床肾脏护理：指南摘要。
Med J Aust. 2023 Oct 16;219(8):374-385. doi: 10.5694/mja2.52114.
4
Electronic health record data quality assessment and tools: a systematic review.电子健康记录数据质量评估及工具：系统综述。
J Am Med Inform Assoc. 2023 Sep 25;30(10):1730-1740. doi: 10.1093/jamia/ocad120.
5
Development and validation of algorithms to identify patients with chronic kidney disease and related chronic diseases across the Northern Territory, Australia.开发和验证算法以识别澳大利亚北领地的慢性肾脏病患者和相关慢性病患者。
BMC Nephrol. 2022 Sep 23;23(1):320. doi: 10.1186/s12882-022-02947-9.
6
Realising the potential: leveraging clinical quality registries for real world clinical research.实现潜力：利用临床质量登记库开展真实世界临床研究。
Med J Aust. 2022 Apr 4;216(6):273-277. doi: 10.5694/mja2.51443. Epub 2022 Mar 10.
7
Competing risks of death and kidney failure in a cohort of Australian adults with severe chronic kidney disease.澳大利亚成年人严重慢性肾脏病队列中死亡和肾衰竭的竞争风险。
Med J Aust. 2022 Feb 21;216(3):140-146. doi: 10.5694/mja2.51361. Epub 2021 Dec 5.
8
Progression and Regression of Chronic Kidney Disease by Age Among Adults in a Population-Based Cohort in Alberta, Canada.加拿大阿尔伯塔省基于人群队列中成年人的慢性肾脏病随年龄进展和消退。
JAMA Netw Open. 2021 Jun 1;4(6):e2112828. doi: 10.1001/jamanetworkopen.2021.12828.
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Dialysis initiation in older persons across centres and over time in Australia and New Zealand.澳大利亚和新西兰各地中心和随时间推移的老年人群透析起始情况。
Nephrology (Carlton). 2021 Jul;26(7):613-622. doi: 10.1111/nep.13873. Epub 2021 Mar 18.
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Estimating the total prevalence and incidence of end-stage kidney disease among Aboriginal and non-Aboriginal populations in the Northern Territory of Australia, using multiple data sources.利用多个数据源估算澳大利亚北领地原住民和非原住民人群终末期肾病的总患病率和发病率。
BMC Nephrol. 2018 Jan 15;19(1):15. doi: 10.1186/s12882-017-0791-3.