Adams Hannah, Salman L, Drinkwater K J, Griffin J, Rowntree S, Howlett D C
Department of Radiology, Eastbourne District General Hospital, Eastbourne, UK.
Department of Radiology, University Hospitals of Bristol and Weston, Bristol, UK.
Osteoporos Int. 2025 Jun;36(6):1069-1076. doi: 10.1007/s00198-025-07488-z. Epub 2025 Apr 22.
To determine the potential economic, morbidity and mortality impact of improvements in reporting of vertebral fragility fractures (VFFs) following a complete audit cycle. Six percent interval increase in reporting of moderate/severe VFFs results in an additional 890 hip fractures predicted in year one and a potential cost saving of £13,207,000.
To determine the potential economic, morbidity and mortality impact of improvements in reporting of vertebral fragility fractures (VFFs) following an initial UK-wide audit initiated by the Royal College of Radiologists (RCR), collaborating with the Royal Osteoporosis Society (ROS) and Royal College of Physicians (RCP) and subsequent re-audit in 2022.
Patient-specific and organisational questionnaires in 2019 and 2022 involved retrospective analysis of between 50 and 100 consecutive, non-traumatic CT studies which included the thoracolumbar spine where the spine was not the area of clinical interest in patients > 70 years. VFFs were recorded and the severity graded using the Genant reporting system. A series of UK-wide interventions were initiated between the audits. Results of the re-audit were evaluated using a bespoke ROS calculator to identify potential patient related and economic benefits from any improvements demonstrated.
Widespread improvements were evident between the two audits across all audit parameters, both patient-related and organisational. Notably, there was a 6% interval increase in reporting of moderate/severe VFFs (26 to 32%). Extrapolating from NHS England data, approximately 1.8 million non-trauma CT studies including the thoracolumbar spine for patients > 70 years were performed in the UK in 2022. The incidence of VFFs in the 2022 audit was found to be 21.7%. Using these figures and the 6% increase, the number of additional patients potentially diagnosed with a VFF equates to 23,420. Applying the ROS Benefits Calculator, in this cohort of 23,420 patients with no treatment, 890 hip fractures can be predicted in year one. With initiation of treatment, this figure falls to 328 patients (562 hip fractures prevented in year one), a potential cost saving of £13,207,000.
The 2022 national re-audit confirmed improvements in radiology diagnostic performance and practice in VFF reporting. Ongoing work is required to build on this improvement and to further embed best practice. To realise this potential, there will need to be significant and maintained investment in onward referral and treatment systems (fracture liaison services or equivalent). Increasing availability of artificial intelligence will significantly increase the diagnoses of these fractures.
为确定在一个完整的审核周期后,椎体脆性骨折(VFF)报告改进所带来的潜在经济、发病率和死亡率影响。中度/重度VFF报告增加6%的区间,预计在第一年将额外增加890例髋部骨折,并可能节省1320.7万英镑的成本。
确定在皇家放射科医师学院(RCR)发起的首次全英范围内审核之后,与皇家骨质疏松症协会(ROS)和皇家内科医师学院(RCP)合作,并在2022年进行后续重新审核后,椎体脆性骨折(VFF)报告改进所带来的潜在经济、发病率和死亡率影响。
2019年和2022年针对患者和机构的问卷涉及对50至100例连续的非创伤性CT研究进行回顾性分析,这些研究包括胸腰椎,而脊柱并非70岁以上患者的临床关注区域。记录VFF并使用Genant报告系统对严重程度进行分级。在两次审核之间启动了一系列全英范围内的干预措施。使用定制的ROS计算器评估重新审核的结果,以确定任何已证明的改进所带来的潜在患者相关和经济效益。
在两次审核之间,所有审核参数(包括与患者相关的和机构的)都有明显的广泛改进。值得注意的是,中度/重度VFF报告增加了6%的区间(从26%增至32%)。根据英国国家医疗服务体系(NHS)英格兰的数据推断,2022年在英国对70岁以上患者进行了约180万例包括胸腰椎的非创伤性CT研究。2022年审核中VFF的发病率为21.7%。使用这些数字和6%的增加率,可能被诊断为VFF的额外患者数量为23420例。应用ROS效益计算器,在这23420例未接受治疗的患者队列中,预计在第一年有890例髋部骨折。开始治疗后,这一数字降至328例患者(第一年预防了562例髋部骨折),可能节省1320.7万英镑的成本。
2022年的全国重新审核证实了放射学诊断性能和VFF报告实践的改进。需要持续开展工作以在此改进基础上进一步巩固最佳实践。为实现这一潜力,需要对转诊和治疗系统(骨折联络服务或类似服务)进行大量且持续的投资。人工智能可用性的提高将显著增加这些骨折的诊断数量。