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英国英格兰多家医院收治的有临床椎体脆性骨折患者的 3 年回顾性分析。

A 3-year retrospective analysis of patients admitted with clinical vertebral fragility fractures across hospitals in England, UK.

机构信息

Healthcare of the Older People, QMC, Nottingham University Hospitals NHS Trust, Nottingham, NG7 2UH, UK.

Centre for Spinal Studies and Surgery, QMC, Nottingham University Hospitals NHS Trust, Nottingham, UK.

出版信息

Osteoporos Int. 2023 Mar;34(3):607-611. doi: 10.1007/s00198-022-06647-w. Epub 2023 Jan 6.

Abstract

UNLABELLED

Our database aimed to assess the impact of vertebral fragility fractures (VFFs) on hospitalisation in England. The results showed that admissions secondary to VFF are increasing annually, more significantly in patients aged 75 years and over. Vertebral augmentation has been showed to reduce length of stay in hospital.

INTRODUCTION

Vertebral fragility fractures (VFFs) are the most common osteoporotic fracture. VFF can result in significant pain requiring hospitalisation. However, there are little data on patient numbers, hospital bed days, and costs, contributed to by these patients.

METHODOLOGY

We report a retrospective analysis of patients aged 55 years and over admitted to hospitals across England from 2017 to 2019. ICD-10 classifications for VFF and OPCS codes were used to identify admissions and patients who had undergone vertebral augmentation (VA).

RESULTS

There were 99,370 patients (61% female) admitted during this period, with 64,370 (65%) patients aged over 75 years. There was a 14.3% average increase in admissions annually. Patients aged over 75 years accounted for 1.5 million bed days, costing £465 million (median length of stay (MLOS) 14.4 days). In comparison, those aged 55-74 years, accounted for 659,000 bed days, costing £239 million (MLOS 10.7 days). The majority of patients (84%) were admitted under a non-surgical speciality and were primarily older (median age 76.8 vs 67.6 years, MLOS 8.2 vs 6.0 days), compared to those admitted to surgical wards 1755 patients underwent vertebral augmentation (VA) (1.8% of the total cohort). The median age of patients undergoing VA was 73.3 years, with 775 (44.2%) of these were aged 75 years and over. In comparison, the median age of patients managed conservatively (non-surgically) was 75.7 years, with 63,595 patients (65.1%) aged 75 years and over. The MLOS and cost per patient admission were lower in the VA group compared to those managed non-surgically.

CONCLUSION

Hospitalised VFF patients represented a significant number, cost, and use of bed days. Those undergoing VA had a significantly shorter length of stay. Further studies are necessary to define those who may benefit from early VA.

摘要

目的

本数据库旨在评估椎体脆性骨折(VFF)对英国住院治疗的影响。结果表明,VFF 导致的入院人数逐年增加,75 岁及以上患者更为显著。椎体增强术已被证明可缩短住院时间。

引言

椎体脆性骨折(VFF)是最常见的骨质疏松性骨折。VFF 可导致严重疼痛,需要住院治疗。然而,由于这些患者的参与,关于患者数量、住院天数和费用的数据很少。

方法

我们报告了对 2017 年至 2019 年期间在英格兰各地医院就诊的 55 岁及以上患者的回顾性分析。使用 ICD-10 分类和 OPCS 代码识别 VFF 入院和接受椎体增强术(VA)的患者。

结果

在此期间有 99370 名患者(61%为女性)入院,其中 64370 名(65%)患者年龄超过 75 岁。每年的入院人数平均增加 14.3%。75 岁以上患者占 150 万张床位,费用 4.65 亿英镑(中位住院时间(MLOS)为 14.4 天)。相比之下,55-74 岁的患者占 659000 张床位,费用 2.39 亿英镑(MLOS 为 10.7 天)。大多数患者(84%)在非外科专科就诊,年龄较大(中位年龄 76.8 岁 vs 67.6 岁,MLOS 为 8.2 天 vs 6.0 天),与在外科病房就诊的 1755 名接受椎体增强术(VA)的患者相比(占总队列的 1.8%)。接受 VA 治疗的患者的中位年龄为 73.3 岁,其中 775 名(44.2%)患者年龄在 75 岁及以上。相比之下,接受非手术治疗(非手术)的患者的中位年龄为 75.7 岁,其中 63595 名(65.1%)患者年龄在 75 岁及以上。VA 组的住院时间和每位患者的住院费用均低于非手术组。

结论

住院 VFF 患者数量多,费用高,占用床位多。接受 VA 的患者住院时间明显缩短。需要进一步研究以确定哪些患者可能受益于早期 VA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55fa/9908666/66e95ad17e69/198_2022_6647_Fig1_HTML.jpg

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