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五氯苯酚中毒：一例致命病例报告，并对临床病程及病理解剖进行评述

Pentachlorophenol intoxication: report of a fatal case, with comments on the clinical course and pathologic anatomy.

作者信息

Gray R E, Gilliland R D, Smith E E, Lockard V G, Hume A S

出版信息

Arch Environ Health. 1985 May-Jun;40(3):161-4. doi: 10.1080/00039896.1985.10545910.

DOI:10.1080/00039896.1985.10545910
PMID:4026386
Abstract

A case of a 33-yr-old man who died following occupational exposure to pentachlorophenol is presented. Postmortem examination revealed cerebral edema and fatty degeneration of the viscera. Review of the literature indicates that the clinical syndrome of poisoning with the compound results from mitochondrial toxicity with derangement of aerobic metabolism.

摘要

本文报告一例33岁男性因职业接触五氯苯酚死亡的病例。尸检发现脑水肿和内脏脂肪变性。文献回顾表明，该化合物中毒的临床综合征是由线粒体毒性导致有氧代谢紊乱引起的。

相似文献

1
Pentachlorophenol intoxication: report of a fatal case, with comments on the clinical course and pathologic anatomy.五氯苯酚中毒：一例致命病例报告，并对临床病程及病理解剖进行评述
Arch Environ Health. 1985 May-Jun;40(3):161-4. doi: 10.1080/00039896.1985.10545910.
2
[Pentachlorophenol and liver-function: a pilot-study on occupationally exposed collectives (author's transl)].[五氯苯酚与肝功能：关于职业暴露群体的初步研究（作者译）]
Int Arch Occup Environ Health. 1981;48(4):347-56. doi: 10.1007/BF00378683.
3
Suspected poisoning by pentachlorophenol in sawdust.
Vet Rec. 1977;101(26-27):525.
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Pentachlorophenol pancreatitis.
Lancet. 1982 Feb 27;1(8270):517. doi: 10.1016/s0140-6736(82)91493-3.
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A pharmacokinetic study of pentachlorophenol poisoning and the effect of forced diuresis.五氯苯酚中毒的药代动力学研究及强制利尿的效果
Clin Toxicol. 1978;12(1):41-8. doi: 10.3109/15563657809149582.
6
Human poisoning with pentachlorophenol and its treatment.五氯苯酚中毒及其治疗
Ecotoxicol Environ Saf. 1977 Dec;1(3):343-7. doi: 10.1016/0147-6513(77)90025-2.
7
Pentachlorophenol poisoning.五氯苯酚中毒
J Occup Med. 1983 Jul;25(7):527-30.
8
Possible pentachlorophenol poisoning in cats.猫可能发生的五氯苯酚中毒
Aust Vet J. 1977 Dec;53(12):602. doi: 10.1111/j.1751-0813.1977.tb15846.x.
9
[Chronic liver disease caused by long term household poisoning with pentachlorophenol].长期家庭接触五氯苯酚中毒所致的慢性肝病
Verh Dtsch Ges Inn Med. 1977;83:1609-11.
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Suspected pentachlorophenol and creosote poisoning.
Mod Vet Pract. 1980 Jan;61(1):53-4.

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Pentachlorophenol-induced cytotoxicity in human erythrocytes: enhanced generation of ROS and RNS, lowered antioxidant power, inhibition of glucose metabolism, and morphological changes.五氯苯酚诱导人红细胞毒性：ROS 和 RNS 生成增加，抗氧化能力降低，葡萄糖代谢抑制，形态改变。
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Pentachlorophenol and the peripheral nervous system: a longitudinal study in exposed workers.
五氯苯酚与外周神经系统：一项针对接触者的纵向研究
Br J Ind Med. 1987 Sep;44(9):638-41. doi: 10.1136/oem.44.9.638.
4
Pentachlorophenol measurements in body fluids of people in log homes and workplaces.
Arch Environ Contam Toxicol. 1989 Jul-Aug;18(4):475-81. doi: 10.1007/BF01055012.