五氯苯酚中毒：一例致命病例报告，并对临床病程及病理解剖进行评述

Pentachlorophenol intoxication: report of a fatal case, with comments on the clinical course and pathologic anatomy.

作者信息

Gray R E, Gilliland R D, Smith E E, Lockard V G, Hume A S

出版信息

Arch Environ Health. 1985 May-Jun;40(3):161-4. doi: 10.1080/00039896.1985.10545910.

DOI:10.1080/00039896.1985.10545910

Abstract

A case of a 33-yr-old man who died following occupational exposure to pentachlorophenol is presented. Postmortem examination revealed cerebral edema and fatty degeneration of the viscera. Review of the literature indicates that the clinical syndrome of poisoning with the compound results from mitochondrial toxicity with derangement of aerobic metabolism.

摘要

本文报告一例33岁男性因职业接触五氯苯酚死亡的病例。尸检发现脑水肿和内脏脂肪变性。文献回顾表明，该化合物中毒的临床综合征是由线粒体毒性导致有氧代谢紊乱引起的。