五氯苯酚中毒及其治疗

Human poisoning with pentachlorophenol and its treatment.

作者信息

Haley T J

出版信息

Ecotoxicol Environ Saf. 1977 Dec;1(3):343-7. doi: 10.1016/0147-6513(77)90025-2.

Abstract

A case of intentional intoxication with pentachlorophenol has been described. Salient features observed included pyrexia, diaphoresis, hyperkinesis, muscle twitching, tremors, epigastric tenderness, leg pain, tachypnea, and tachycardia. The patient's restlessness and agitation were controlled with phenytoin and phenobarbital. Forced diuresis with furosemide and mannitol resulted in a large increase in urinary excretion of pentachlorophenol. It is suggested that such therapy may be life saving in such intoxications.

摘要

已描述了一例故意摄入五氯苯酚中毒的病例。观察到的显著特征包括发热、出汗、运动亢进、肌肉抽搐、震颤、上腹部压痛、腿痛、呼吸急促和心动过速。患者的烦躁不安通过苯妥英钠和苯巴比妥得到控制。使用速尿和甘露醇进行强制利尿导致五氯苯酚的尿排泄量大幅增加。建议这种治疗方法在这类中毒情况中可能挽救生命。