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险中求生:原发性心脏淋巴瘤伴局部区域淋巴结受累并合并心包积液和心律失常

Surviving the Odds: Primary Cardiac Lymphoma With Locoregional Lymph Node Involvement Complicated by Pericardial Effusion and Arrhythmia.

作者信息

Bachour Kinan, Shah Sagar, Reichl Allison, Chia Jennifer, Shabsovich David S, Castillo Adrian, Cho Geoffrey

机构信息

Department of Cardiology, University of California Los Angeles, Los Angeles, USA.

Department of Gastroenterology, University of California Los Angeles, Los Angeles, USA.

出版信息

Cureus. 2025 Mar 22;17(3):e81012. doi: 10.7759/cureus.81012. eCollection 2025 Mar.

Abstract

Primary cardiac lymphoma (PCL) is a rare malignant disease and its presentation varies depending on the degree of infiltration and location in the myocardium; hence its diagnosis can be challenging. We present a case of a 67-year-old otherwise healthy male who initially presented with recurrent syncope found to have a pericardial effusion and complete heart block. Paratracheal biopsy of a fluorodeoxyglucose (FDG)-avid lymph node was consistent with diffuse large B-cell lymphoma. Diagnosis is usually identified histologically, but imaging is key in guiding biopsy and monitoring disease regression. Chemotherapy is the mainstay of treatment. In this case report, we present a unique presentation of primary cardiac lymphoma presenting as complete heart block with extra-cardiac lymph node involvement and review its management.

摘要

原发性心脏淋巴瘤(PCL)是一种罕见的恶性疾病,其表现因心肌浸润程度和位置而异;因此,其诊断可能具有挑战性。我们报告一例67岁的健康男性,最初表现为反复晕厥,发现有心包积液和完全性心脏传导阻滞。对氟脱氧葡萄糖(FDG)摄取阳性的气管旁淋巴结进行活检,结果与弥漫性大B细胞淋巴瘤一致。诊断通常通过组织学确定,但影像学在指导活检和监测疾病消退方面至关重要。化疗是主要的治疗方法。在本病例报告中,我们展示了原发性心脏淋巴瘤以完全性心脏传导阻滞伴心脏外淋巴结受累的独特表现,并对其治疗进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9224/12011517/a995420e1736/cureus-0017-00000081012-i01.jpg

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