Johri Amer, Baetz Tara, Isotalo Phillip A, Nolan Robert L, Sanfilippo Anthony J, Ropchan Glorianne
Department of Medicine, Queen's University, Kingston, Canada.
Can J Cardiol. 2009 Jun;25(6):e210-2. doi: 10.1016/s0828-282x(09)70110-2.
Primary cardiac lymphomas are rare extranodal lymphomas that should be distinguished from secondary cardiac involvement by disseminated non-Hodgkin's lymphoma. Cardiac lymphomas often mimic other cardiac neoplasms, including myxomas and angiosarcomas, and often require multimodality cardiac imaging, in combination with endomyocardial biopsy, excisional biopsy or pericardial fluid cytology, to establish a definitive diagnosis. A 60-year-old immunocompetent man who presented with superior vena cava syndrome secondary to a right atrial, primary cardiac diffuse large B cell lymphoma (non-Hodgkin's lymphoma) is described in the present article. The patient had no clinical evidence of disseminated lymphoma and was successfully treated with prompt surgical excision of his atrial mass, followed by anthracycline-based chemotherapy. The patient required multi-modality cardiac imaging to accurately identify and plan surgical excision of his cardiac lymphoma. The therapeutic management and clinical and radio-logical features of primary cardiac lymphoma are reviewed.
原发性心脏淋巴瘤是罕见的结外淋巴瘤，应与弥漫性非霍奇金淋巴瘤引起的继发性心脏受累相鉴别。心脏淋巴瘤常与其他心脏肿瘤相似，包括黏液瘤和血管肉瘤，通常需要多模态心脏成像，并结合心内膜活检、切除活检或心包积液细胞学检查，以明确诊断。本文描述了一名60岁免疫功能正常的男性，因右心房原发性心脏弥漫性大B细胞淋巴瘤（非霍奇金淋巴瘤）继发上腔静脉综合征。该患者无弥漫性淋巴瘤的临床证据，通过及时手术切除心房肿块，随后进行以蒽环类药物为基础的化疗，成功治愈。该患者需要多模态心脏成像来准确识别并规划其心脏淋巴瘤的手术切除。本文对原发性心脏淋巴瘤的治疗管理以及临床和影像学特征进行了综述。
