Lucchini Elisa, Merlo Marco, Ballerini Mario, Porcari Aldostefano, Sinagra Gianfranco, Pagnan Lorenzo, Rensi Marco, Romano Andrea, Bussani Rossana, Ballotta Laura, Zaja Francesco
S.C. Ematologia, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.
S.C. Cardiologia, Dipartimento Cardiotoracovascolare, Centro per la Diagnosi e Cura delle Cardiomiopatie, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.
Front Oncol. 2021 Apr 27;11:665736. doi: 10.3389/fonc.2021.665736. eCollection 2021.
Cardiac lymphomas are rare extranodal lymphomas involving primarily and secondarily the heart and/or pericardium. Here we describe three cases of cardiac involvement from lymphoma with specific peculiarities: two primary cardiac Diffuse Large B-cell Lymphomas and one secondary involvement from Marginal Zone Lymphoma (MZL). The first case highlights the issue of early CNS relapse and the possible role for CNS prophylaxis; the second case demonstrates the difficulties of interpretation and possible mistakes of different radiologic techniques adopted to evaluate cardiac involvement by lymphoma during follow-up; the third is a unique case of MZL with cardiac involvement. Our aim is to share the findings observed in these cases putting them in relation with data from the literature.
心脏淋巴瘤是罕见的结外淋巴瘤，主要或次要累及心脏和/或心包。在此，我们描述三例具有特殊特征的淋巴瘤累及心脏的病例：两例原发性心脏弥漫性大B细胞淋巴瘤和一例边缘区淋巴瘤（MZL）的继发性累及。第一例突出了早期中枢神经系统复发的问题以及中枢神经系统预防的可能作用；第二例展示了在随访期间评估淋巴瘤累及心脏所采用的不同放射学技术在解读上的困难及可能出现的错误；第三例是MZL累及心脏的独特病例。我们的目的是分享在这些病例中观察到的发现，并将其与文献数据相关联。
