Wretman C, Risberg A, Grönlund H, Edner A
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Department of Health, Education and Technology, Lulea University of Technology, Lulea, Sweden.
Acta Paediatr. 2025 Sep;114(9):2322-2328. doi: 10.1111/apa.70112. Epub 2025 Apr 23.
Allergies are a potential risk when introducing dogs in health care. Therefore, I chose to evaluate if allergen levels in Hospital Dogs can be reduced by washing the dogs and thereby develop patient-safe guidelines when implicating Hospital Dogs in Swedish hospitals.
Samples (n = 29) were taken from the dog's fur before and after washing and after the Hospital Dog/child meeting to investigate change in allergens. Further samples were taken when washing with two different shampoos, measuring how long decreased levels of allergens lasted. The dog allergens Can f 1 and Can f 4 were analysed by competitive ELISA.
The mean allergen concentration of Can f 1 decreased from 21.8 ± 11.2 ng/mL before wash to 5.8 ± 3.7 ng/mL (p < 0.0001) after wash. Both types of shampoo resulted in a reduction of Can f 1 and Can f 4 and remained low for three days.
By washing the Hospital Dogs with shampoo, we have found a significant reduction of the dog allergen Can f 1 and Can f 4 lasting for at least three days. In the work of introducing certified Hospital Dogs into Swedish hospitals, which so far has not been possible in Sweden, this is an important finding.
在医疗保健中引入犬只时，过敏是一个潜在风险。因此，我选择评估通过给犬只洗澡是否可以降低医院犬的过敏原水平，从而在瑞典医院引入医院犬时制定患者安全指南。
在洗澡前后以及医院犬与儿童互动后采集犬只毛发样本（n = 29），以调查过敏原的变化。在用两种不同洗发水洗澡时采集更多样本，测量过敏原水平降低持续的时间。通过竞争ELISA分析犬过敏原Can f 1和Can f 4。
Can f 1的平均过敏原浓度从洗澡前的21.8±11.2 ng/mL降至洗澡后的5.8±3.7 ng/mL（p < 0.0001）。两种洗发水都使Can f 1和Can f 4减少，并在三天内保持低水平。
通过用洗发水给医院犬洗澡，我们发现犬过敏原Can f 1和Can f 4显著减少，且至少持续三天。在瑞典将认证医院犬引入医院的工作中（瑞典目前尚未实现），这是一项重要发现。
