Nilasari Hanny, Miranda Eliza, Marissa Melani, Ruspitawati Ani, Handayani Dwi O T L, Salama Ngabila, Setiawan Budi, Aisyah Tiranti V, Haq Arif S, Zuhroh Siti, Safitri Eka Y, Pramono Rahmat A, Wisnuwardani Inggrita, Nelwan Erni J, Sinto Robert, Susilo Adityo, Saharman Yulia R, Ratnoglik Suratno L, Pitawati Ni L P, Fauzan Muhammad, Hasanah Sekar S A, Sharasti Megandhita, Yunihastuti Evy
Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.
Department of Dermatology and Venereology, University of Indonesia, Jakarta 10430, Indonesia.
Vaccines (Basel). 2025 Feb 20;13(3):210. doi: 10.3390/vaccines13030210.
BACKGROUND/OBJECTIVE: This study explores the epidemiology and clinical features of re-emerging mpox in Jakarta, Indonesia.
This study used a retrospective study design to describe the epidemiological data, clinical features, and mortality of mpox patients from August 2022 to December 2023. In addition, this study also aims to identify the differences in both the epidemiology and clinical features of mpox in people living with HIV (PLHIV) and in non-HIV patients (non-PLHIV).
Our study shows that, as of the end of December 2023, 59 mpox cases were treated in Jakarta. All of the mpox cases in Jakarta were diagnosed in males, mainly found in MSM (91.5%), and PLHIV (78%). Most patients would manifest with fever, rash, and skin lesions. Syphilis was found as a concomitant infection in this group (22/59, 37.2%). Severe manifestations were found among PLHIV without antiretroviral therapy (ART).
Mpox cases in Jakarta were all found in males and most of them were PLHIV. There are various manifestations of mpox; however, since immunosuppressed patients could present differently, a strong surveillance and vaccine notification system, cautious management, and spreading vaccination awareness are needed to prevent and treat mpox.
背景/目的：本研究探讨印度尼西亚雅加达再次出现的猴痘的流行病学和临床特征。
本研究采用回顾性研究设计，描述2022年8月至2023年12月期间猴痘患者的流行病学数据、临床特征和死亡率。此外，本研究还旨在确定艾滋病病毒感染者（PLHIV）和非艾滋病病毒患者（非PLHIV）中猴痘在流行病学和临床特征方面的差异。
我们的研究表明，截至2023年12月底，雅加达共治疗了59例猴痘病例。雅加达所有猴痘病例均为男性，主要见于男男性行为者（91.5%）和艾滋病病毒感染者（78%）。大多数患者会出现发热、皮疹和皮肤病变。该组中发现梅毒为合并感染（22/59，37.2%）。在未接受抗逆转录病毒治疗（ART）的艾滋病病毒感染者中发现了严重表现。
雅加达的猴痘病例均为男性，其中大多数为艾滋病病毒感染者。猴痘有多种表现；然而，由于免疫抑制患者的表现可能不同，因此需要强大的监测和疫苗通报系统、谨慎的管理以及提高疫苗接种意识来预防和治疗猴痘。
