Liu Di, Shimizu Muneshige
Graduate School of Science and Technology, Tokai University, 3-20-1 Orido, Shimizu, 424- 8610, Shizuoka, Japan.
Institute Oceanic Research and Development, Tokai University, 3-20-1 Orido, Shimizu, 424- 8610, Shizuoka, Japan.
Sci Rep. 2025 Apr 23;15(1):14041. doi: 10.1038/s41598-025-96393-w.
Recently, the presence of microplastics (MPs) in common foods such as salt and beverages has been widely reported Microplastics (MPs) have been widely reported in common foods, including salt and beverages. MPs spread through the food chain and are eventually ingested into the human body through the diet. They have been found to accumulate in human feces, blood, and liver tissues, raising concerns about the effects of continuous intake of foods containing MP on the body. We examined whether rats could rapidly excrete polyethylene MPs (average particle size of 200 μm) when the MPs and were mixed with non-digestive dietary materials in their feed (indigestible dextrin, lactosucrose, chitosan, and eggshell membrane proteins). The group that ingested chitosan showed significant changes, including increased fecal weight, increased MP excretion rate, and decreased intestinal MP retention rate. The MP excretion rates in feces 0-144 h after ingestion were 83.7% ± 3.8% in the control group and 115.6% ± 4.5% in the chitosan group. These findings indicate that chitosan effectively promotes the expulsion of polyethylene MPs. The addition of chitosan to food may reduce the potential harm caused by MPa to a variety of organisms, including humans.
最近，盐和饮料等常见食品中微塑料（MPs）的存在已被广泛报道。微塑料已在包括盐和饮料在内的常见食品中被广泛报道。微塑料通过食物链传播，最终通过饮食摄入人体。人们发现它们在人类粪便、血液和肝脏组织中积累，这引发了人们对持续摄入含有微塑料的食物对身体影响的担忧。我们研究了大鼠在饲料中将微塑料与非消化性膳食材料（难消化糊精、乳糖蔗糖、壳聚糖和蛋壳膜蛋白）混合时，是否能快速排出平均粒径为200μm的聚乙烯微塑料。摄入壳聚糖的组出现了显著变化，包括粪便重量增加、微塑料排泄率提高和肠道微塑料保留率降低。摄入后0至144小时粪便中的微塑料排泄率，对照组为83.7%±3.8%，壳聚糖组为115.6%±4.5%。这些发现表明壳聚糖能有效促进聚乙烯微塑料的排出。在食物中添加壳聚糖可能会降低微塑料对包括人类在内的多种生物造成的潜在危害。
