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一名年轻健康女性因化脓性甲状腺炎导致的可逆性甲状腺毒症

Reversible Thyrotoxicosis Caused by Suppurative Thyroiditis in a Young Healthy Woman.

作者信息

Sert Begüm Süeda, Tummers-de Lind van Wijngaarden Roderick F A, Buijs Jacqueline

机构信息

Department of Internal Medicine, Zuyderland Medical Centre, Heerlen, The Netherlands.

出版信息

Eur J Case Rep Intern Med. 2025 Mar 10;12(4):005101. doi: 10.12890/2025_005101. eCollection 2025.

DOI:10.12890/2025_005101
PMID:40270664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12013232/
Abstract

INTRODUCTION

Acute suppurative thyroiditis is a bacterial infection of the thyroid gland. Potential risk factors are an immunocompromised state or the presence of pre-existing thyroid disease. Acute suppurative thyroiditis may be complicated by abscess formation and/or thyrotoxicosis, which are both rare but potentially life-threatening complications.

CASE DESCRIPTION

We describe a case of acute suppurative thyroiditis secondary to tonsillitis in a 22-year-old healthy female presenting with thyrotoxicosis due to abscess formation. She presented with complaints of palpitations, fever, extreme salivation, dysphagia, pain and swelling of the neck. Further analysis revealed a sinus tachycardia, high inflammatory parameters, and clinical and biochemical signs of thyrotoxicosis. Computed tomography showed abscess formation in the left lobe of the thyroid gland with extension to the retropharyngeal space and deviation of the trachea to the contralateral side. Blood cultures were positive for and . The patient was treated with antibiotics and underwent an operative excision and drainage of the abscess and recovered well. Symptomatic thyrotoxicosis was treated with metoprolol. has not previously been implicated in causing acute bacterial thyroiditis.

CONCLUSION

Acute suppurative thyroiditis may occur in healthy young adults without any predisposing factors. Concomitant thyrotoxicosis is rare, but important to diagnose. Bacterial thyroiditis may be either a primary thyroid infection or a secondary complication of a severe tonsillitis. Early recognition and treatment are of great importance to reduce overall mortality and morbidity, and to prevent the development of complications.

LEARNING POINTS

Suppurative thyroiditis can lead to overt but potentially reversible thyrotoxicosis.Bacterial thyroiditis can occur in healthy young adults, although immune compromised patients and patients with anatomical variants are more susceptible.Acute suppurative thyroiditis is usually associated with a euthyroid state.

摘要

引言

急性化脓性甲状腺炎是甲状腺的细菌感染。潜在危险因素为免疫功能低下状态或既往存在的甲状腺疾病。急性化脓性甲状腺炎可能并发脓肿形成和/或甲状腺毒症,这两种情况虽罕见但均可能危及生命。

病例描述

我们报告一例22岁健康女性因扁桃体炎继发急性化脓性甲状腺炎,因脓肿形成出现甲状腺毒症。她主诉心悸、发热、流涎过多、吞咽困难、颈部疼痛和肿胀。进一步分析显示窦性心动过速、炎症指标升高以及甲状腺毒症的临床和生化体征。计算机断层扫描显示甲状腺左叶有脓肿形成,并延伸至咽后间隙,气管向对侧移位。血培养 和 呈阳性。患者接受了抗生素治疗,并接受了脓肿的手术切除和引流,恢复良好。有症状的甲状腺毒症用美托洛尔治疗。此前 未被认为可导致急性细菌性甲状腺炎。

结论

急性化脓性甲状腺炎可发生于无任何易感因素的健康年轻成年人。并发甲状腺毒症虽罕见,但诊断很重要。细菌性甲状腺炎可能是原发性甲状腺感染或严重扁桃体炎的继发性并发症。早期识别和治疗对于降低总体死亡率和发病率以及预防并发症的发生非常重要。

学习要点

化脓性甲状腺炎可导致明显但可能可逆的甲状腺毒症。细菌性甲状腺炎可发生于健康年轻成年人,尽管免疫功能低下患者和有解剖变异的患者更易患病。急性化脓性甲状腺炎通常与甲状腺功能正常状态相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/098c/12013232/39a26cc1f05e/5101_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/098c/12013232/39a26cc1f05e/5101_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/098c/12013232/39a26cc1f05e/5101_Fig1.jpg

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