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[具体内容]在神经退行性疾病中的作用:当前证据与未来方向。 (注:原文中“Role of ”后面缺少具体内容)

Role of in neurodegenerative diseases: current evidence and future directions.

作者信息

Luo Huaiqing, Wei Siwen, Fu Shujun, Han Li

机构信息

Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province, Hunan Normal University Health Science Center, Changsha, Hunan, China.

Institute of Interdisciplinary Studies, Hunan Normal University Health Science Center, Changsha, Hunan, China.

出版信息

Front Pharmacol. 2025 Apr 9;16:1511011. doi: 10.3389/fphar.2025.1511011. eCollection 2025.

Abstract

Neurodegenerative diseases are caused by the progressive degeneration of neurons and/or their myelin sheaths, ultimately leading to cognitive and motor dysfunction. Due to their complex pathogenesis and the limited efficacy of therapeutic drugs, these diseases have attracted significant attention. , belongs to family Amaranthaceae, has been extensively used in the traditional and folk medicines for the treatment of various ailments. Modern research has revealed that possesses various pharmacological effects, including cardiocerebrovascular protection, immune regulation, antioxidation, and anti-aging. Furthermore, the neuroprotective effects of have been confirmed by numerous scientific studies. This review focuses on the primary pharmacological effects and mechanisms of in the prevention and treatment of neurodegenerative diseases, as well as their potential application prospects. This review aims to provide insights into the potential clinical applications and research directions of in neurodegenerative diseases.

摘要

神经退行性疾病是由神经元和/或其髓鞘的进行性退化引起的,最终导致认知和运动功能障碍。由于其复杂的发病机制以及治疗药物疗效有限,这些疾病已引起了广泛关注。 ,属于苋科,已被广泛用于传统和民间药物中治疗各种疾病。现代研究表明 具有多种药理作用,包括心脑血管保护、免疫调节、抗氧化和抗衰老。此外, 对神经的保护作用已得到众多科学研究的证实。本综述重点关注 在预防和治疗神经退行性疾病中的主要药理作用和机制,以及它们的潜在应用前景。本综述旨在深入了解 在神经退行性疾病中的潜在临床应用和研究方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea12/12014640/7201fc6abead/fphar-16-1511011-g001.jpg

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