Oleniacz-Trawińska Monika, Kotela Agnieszka, Kensy Julia, Kiryk Sylwia, Dobrzyński Wojciech, Kiryk Jan, Gerber Hanna, Fast Magdalena, Matys Jacek, Dobrzyński Maciej
Medical Center of Innovation LLC, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.
Faculty of Dentistry, Wroclaw Medical University, 50-425 Wroclaw, Poland.
Materials (Basel). 2025 Apr 2;18(7):1627. doi: 10.3390/ma18071627.
This systematic review evaluates the evidence on factors affecting fluoride release from compomer restorative materials to provide clinicians with insights for optimizing their use in caries prevention.
In February 2025, an extensive digital search was conducted across reputable databases such as PubMed, Web of Science, and Scopus. The search utilized carefully chosen keywords: "fluoride release" AND "compomer" and followed the PRISMA guidelines. Initially, 287 articles were identified, but after applying the inclusion criteria, 34 studies were selected for review.
This review found that fluoride release from compomers follows an initial burst phase before stabilizing at lower levels. Fifteen studies proved that compomers release less fluoride than glass ionomer cements but more than composite resins, as concluded from six studies. The release rate is significantly influenced by pH, with acidic conditions enhancing fluoride diffusion. Some studies also highlighted the potential for fluoride recharge through external applications such as toothpaste or varnish.
Compomer restorative materials offer a steady, moderate fluoride release that supports caries prevention. Their effectiveness is enhanced in acidic environments, supporting their use in high-risk patients.
本系统评价评估了影响复合树脂修复材料氟释放的因素的证据，为临床医生在预防龋齿中优化其使用提供见解。
2025年2月，在PubMed、科学网和Scopus等知名数据库中进行了广泛的数字检索。检索使用了精心挑选的关键词：“氟释放”和“复合树脂”，并遵循PRISMA指南。最初识别出287篇文章，但在应用纳入标准后，选择了34项研究进行综述。
本综述发现，复合树脂的氟释放在稳定在较低水平之前经历一个初始突发阶段。15项研究证明，复合树脂释放的氟比玻璃离子粘固剂少，但比复合树脂多，这是6项研究得出的结论。释放速率受pH值的显著影响，酸性条件会增强氟的扩散。一些研究还强调了通过牙膏或清漆等外部应用进行氟再充注的可能性。
复合树脂修复材料提供稳定、适度的氟释放，有助于预防龋齿。它们在酸性环境中的有效性增强，支持其在高危患者中的使用。
