Barbosa Carolina Pelegrini, Stefanini Francisco Rosa, Penha Fernando, Góes Miguel Ângelo, Draibe Sérgio Antonio, Canziani Maria Eugênia, Paranhos Junior Augusto
Ophthalmology Department, Universidade Federal de São Paulo, Brazil.
Arq Bras Oftalmol. 2011 Mar-Apr;74(2):106-9. doi: 10.1590/s0004-27492011000200007.
To evaluate the intraocular pressure and ocular perfusion pressure during a hemodialysis.
Sixty-seven eyes from thirty-five patients were evaluated at the beggining of hemodialysis, 2 hours and 4 hours after initiation. Intraocular pressure was evaluated using a Tonopen. Systolic and diastolic arterial pressures were measured with a manual sphygmomanometer. The ocular perfusion pressure was estimated by measuring the difference between 2/3 of the mean arterial pressure and the intraocular pressure values. Generalized estimating equations were used to evaluate the difference between the repeated measurements using the appropriate correction for inter-eye dependency.
There was no statistically significant difference in ocular perfusion pressure, in intraocular pressure (p=0.93) and in systolic arterial pressure (p=0.92) at the three time points (p=0.69). But, when analyzing the extreme values, some patients exhibited lower diastolic perfusion pressures at all time points.
Our results did not support the view that significant changes in ocular perfusion pressure and intraocular pressure occur during hemodialysis session. However, we observed that some patients exhibited lower diastolic perfusion pressures, which could be a poor prognostic factor for glaucoma patients.
评估血液透析期间的眼压和眼灌注压。
对35例患者的67只眼在血液透析开始时、开始后2小时和4小时进行评估。使用眼压计评估眼压。用手动血压计测量收缩压和舒张压。通过测量平均动脉压的2/3与眼压值之间的差值来估算眼灌注压。使用广义估计方程，通过对眼间相关性进行适当校正来评估重复测量之间的差异。
在三个时间点，眼灌注压、眼压（p = 0.93）和收缩压（p = 0.92）均无统计学显著差异（p = 0.69）。但是，在分析极值时，一些患者在所有时间点的舒张压灌注压均较低。
我们的结果不支持血液透析期间眼灌注压和眼压会发生显著变化的观点。然而，我们观察到一些患者的舒张压灌注压较低，这可能是青光眼患者的一个不良预后因素。
