Zhang Guiyun, Lai Zhiwei, Xie Jianhua, Yang Weiqiang
Fujian Provincial Collaborative Innovation Institute of Food Industry Technology, Zhangzhou Institute of Technology, Zhangzhou, 363000, China.
Fujian Provincial Key Laboratory of Pollution Monitoring and Control, Fujian Provincial Key Laboratory of Modern Analytical Science and Separation Technology, College of Chemistry, Chemical Engineering and Environment, Minnan Normal University, 36 Xianqian Street, Zhangzhou, Fujian, 363000, P. R. China.
Mikrochim Acta. 2025 Apr 24;192(5):318. doi: 10.1007/s00604-025-07169-y.
Methylmercury (CHHg), a lipophilic environmental pollutant, accumulates in fish, shellfish, and other organisms, posing significant risks to human health through the food chain. Developing a convenient and sensitive analytical method for CHHg detection is crucial for reducing costs and enhancing the efficiency of food safety testing. In this study, we prepared an octyl-modified silica isoporous membrane on the indium tin oxide (ITO) electrode (Octyl-SIM/ITO) via the electrochemical-assisted self-assembly (EASA) method using octyltrimethoxysilane (O-TES) as the functional organosilane. The Octyl-SIM/ITO electrode exhibits vertically-ordered nanochannels and strong hydrophobic affinity, enabling selective penetration and enrichment of weakly polar analytes. Utilizing square wave anodic stripping voltammetry (SWASV), the Octyl-SIM/ITO electrode demonstrates superior electrochemical response signals for CHHg detection, achieving a detection limit as low as 4 nM. This method allows for accurate and reproducible detection of CHHg in fish and oyster samples with minimal sample preparation, offering promising potential for portable in situ detection.
甲基汞(CHHg)是一种亲脂性环境污染物,会在鱼类、贝类及其他生物体中蓄积,通过食物链对人类健康构成重大风险。开发一种便捷且灵敏的CHHg检测分析方法对于降低成本和提高食品安全检测效率至关重要。在本研究中,我们以辛基三甲氧基硅烷(O-TES)作为功能性有机硅烷,通过电化学辅助自组装(EASA)方法在氧化铟锡(ITO)电极上制备了辛基修饰的二氧化硅等孔膜(Octyl-SIM/ITO)。Octyl-SIM/ITO电极具有垂直排列的纳米通道和很强的疏水亲和力,能够实现弱极性分析物的选择性渗透和富集。利用方波阳极溶出伏安法(SWASV),Octyl-SIM/ITO电极对CHHg检测展现出优异的电化学响应信号,检测限低至4 nM。该方法能够在极少样品前处理的情况下,对鱼类和牡蛎样品中的CHHg进行准确且可重复的检测,为便携式原位检测提供了广阔的应用前景。