Tabata Aki, Yabe Hiroki, Katogi Takehide, Mitake Yuya, Oono Shunta, Fujii Takayuki
Department of Rehabilitation, Seirei Sakura Citizen Hospital, Chiba, Japan.
Department of Physical Therapy, School of Rehabilitation Sciences, Seirei Christopher University, Shizuoka, Japan.
Ther Apher Dial. 2025 Apr 24. doi: 10.1111/1744-9987.70026.
This study aimed to investigate the factors associated with hospitalization in older patients with pre-dialysis CKD, including physical function.
This single-center, prospective cohort study included 111 patients aged ≥65 years with stage 3-5 non-hemodialyzed CKD. Physical function was assessed using the short physical performance battery (SPPB), 10-m walk test, and grip strength test. Hospitalizations and reasons for readmission were tracked from discharge to the end of the follow-up period.
Kaplan-Meier analysis showed significant associations between rehospitalization and SPPB, 10-meter walk speed, and grip strength. The cutoff values predicting rehospitalization were 11 points for SPPB, 1.1 m/s for 10-meter walk speed, and 31 kg for grip strength. Multivariate Cox regression revealed that SPPB, hemoglobin, and estimated glomerular filtration rate (eGFR) were independently associated with rehospitalization risk.
SPPB may predict hospitalization in older pre-dialysis CKD patients, emphasizing the importance of screening and preventing physical function decline.
本研究旨在调查透析前慢性肾脏病（CKD）老年患者住院的相关因素，包括身体功能。
这项单中心前瞻性队列研究纳入了111例年龄≥65岁的3-5期非血液透析CKD患者。使用简短体能状况量表（SPPB）、10米步行试验和握力试验评估身体功能。从出院到随访期结束，追踪住院情况和再次入院原因。
Kaplan-Meier分析显示再次住院与SPPB、10米步行速度和握力之间存在显著关联。预测再次住院的临界值为SPPB 11分、10米步行速度1.1米/秒和握力31千克。多变量Cox回归显示，SPPB、血红蛋白和估计肾小球滤过率（eGFR）与再次住院风险独立相关。
SPPB可能预测透析前CKD老年患者的住院情况，强调了筛查和预防身体功能下降的重要性。
