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追求以患者为中心的医学:2型糖尿病患者如何选择降糖药物?一项定性研究。

In Pursuit of Person-Centered Medicine: How Do People with Type 2 Diabetes Choose Glucose-Lowering Medications? A Qualitative Study.

作者信息

Golembiewski Elizabeth H, Ning Xinyuan, Mickelson Mindy M, Gockerman Janet P, Tesulov Michael, Labatte Bertina, McCoy Rozalina G

机构信息

Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.

Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.

出版信息

J Gen Intern Med. 2025 Apr 24. doi: 10.1007/s11606-025-09509-3.

Abstract

BACKGROUND

Clinical guidelines recommend person-centered selection of glucose-lowering therapies that takes patient goals, preferences, and needs into consideration. However, there is limited understanding of how patients' preferences and experiences shape their medication choices.

OBJECTIVE

To explore how individuals with type 2 diabetes (T2D) choose glucose-lowering medications, focusing on their treatment goals, preferences, and alignment between patient and clinician priorities.

DESIGN

Qualitative study.

PARTICIPANTS

Forty adults with T2D at moderate cardiovascular disease risk, currently taking ≥ 1 glucose-lowering medication, recruited from two health systems in the Midwestern and Southern United States.

APPROACH

Semi-structured individual interviews were conducted to explore factors influencing medication choice, quality of communication with clinicians, and degree of patient-perceived alignment between patient and clinician treatment goals.

KEY RESULTS

Among the 40 participants, 55% were female with a mean age of 56.1 years (SD 13.6). The majority identified as White (50.0%) or Black (37.5%). Participants emphasized the importance of avoiding specific side effects and achieving efficacy in their T2D medication choices. While participants valued clear and comprehensive information about medications from clinicians, many described unmet needs and often supplemented clinical information with advice from peers and online sources. Perceptions around medication decision-making authority varied, with some participants preferring patient-led choices, others relying on clinician expertise, and many advocating for a collaborative or shared decision-making approach to selecting a T2D medication. Discrepancies were noted between clinical priorities and person-centered outcomes, with patients prioritizing quality of life and manageable treatment regimens over strict clinical targets.

CONCLUSIONS

Understanding patient preferences and experiences is crucial for achieving person-centeredness in T2D medication management. Participants described diverse approaches to evaluating glucose-lowering medications, prioritizing quality of life, ease of adherence, and minimizing side effects. Transparent and collaborative communication with clinicians was identified as crucial for aligning treatment plans with patient values.

摘要

背景

临床指南建议以患者为中心选择降糖治疗方案,需考虑患者的目标、偏好和需求。然而,对于患者的偏好和经历如何影响其药物选择,人们了解有限。

目的

探讨2型糖尿病(T2D)患者如何选择降糖药物,重点关注其治疗目标、偏好以及患者与临床医生优先事项的一致性。

设计

定性研究。

参与者

从美国中西部和南部的两个医疗系统招募了40名患有中度心血管疾病风险的T2D成年患者,他们目前正在服用≥1种降糖药物。

方法

进行半结构化个体访谈,以探讨影响药物选择的因素、与临床医生的沟通质量以及患者感知的患者与临床医生治疗目标的一致程度。

主要结果

在40名参与者中,55%为女性,平均年龄为56.1岁(标准差13.6)。大多数人认定为白人(50.0%)或黑人(37.5%)。参与者强调在选择T2D药物时避免特定副作用和实现疗效的重要性。虽然参与者重视临床医生提供的关于药物的清晰和全面信息,但许多人表示需求未得到满足,并且经常用同行和在线来源的建议补充临床信息。关于药物决策权威的看法各不相同,一些参与者更喜欢由患者主导选择,另一些人依赖临床医生的专业知识,许多人主张采用协作或共同决策的方法来选择T2D药物。临床优先事项与以患者为中心的结果之间存在差异,患者将生活质量和易于管理的治疗方案置于严格的临床目标之上。

结论

了解患者的偏好和经历对于在T2D药物管理中实现以患者为中心至关重要。参与者描述了评估降糖药物的不同方法,将生活质量、依从性和最小化副作用作为优先事项。与临床医生进行透明和协作的沟通被认为对于使治疗计划与患者价值观保持一致至关重要

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