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瑞典老年人自评健康相关因素的年龄变化——来自1930年出生的哥德堡H70研究队列的结果

Age-related changes in factors associated with self-rated health in Swedish older adults- findings from the Gothenburg H70 study cohort born 1930.

作者信息

Thörnqvist Karolina, Johansson Lena, Solevid Maria, Berg Anne Ingeborg, Skoog Ingmar, Falk Erhag Hanna

机构信息

Neuropsychiatric Epidemiology Unit, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Centre for Ageing and Health (AgeCap), University of Gothenburg, Gothenburg, Sweden.

出版信息

BMC Geriatr. 2025 Apr 24;25(1):275. doi: 10.1186/s12877-025-05923-8.

Abstract

BACKGROUND

Knowledge about age-related changes in factors associated with self-rated health (SRH) in older adults is still limited.

OBJECTIVE

To explore changes in SRH and analyze the strength of the association between different factors and SRH at ages 70, 75, 85, and 88 in a cohort born in 1930.

DESIGN

Cross-sectional.

SETTING

The Gothenburg H70 Birth Cohort Studies.

SUBJECTS

939 individuals, providing 1841 observations.

METHOD

SRH was assessed using the same question at every examination. Factors potentially affecting SRH included somatic and mental disease burden, functional ability, life satisfaction, and loneliness. Lung function was included as an indicator of physical fitness. Descriptive statistics and binary regression were used to explore cohort characteristics, associated factors, and SRH. GLMM (Generalized linear mixed model) was used to perform a sensitivity analysis and test the robustness of our results.

RESULTS

There was an association between factors and SRH at every age, except feelings of loneliness and having a low disease burden at 85. High disease burden showed the strongest association at 70 and the weakest at 85. Depression showed the strongest association at 85 and the lowest at 88. When also controlling for life satisfaction, the associations changed between the ages, and feelings of loneliness were no longer associated with poor SRH other than at 88. The association between factors and poor SRH was generally stronger at ages 70-75 than at ages 85-88. The sensitivity analysis using GLMM confirmed the robustness of our results.

CONCLUSION

The proportion of poor SRH decreases with age despite a higher frequency of somatic health conditions. Associated factors varied across ages, indicating that physical factors more strongly influence SRH in younger-old adults, while psychosocial factors have a greater impact on SRH in older-old adults.

摘要

背景

关于老年人自评健康(SRH)相关因素随年龄变化的知识仍然有限。

目的

探讨1930年出生队列中70岁、75岁、85岁和88岁时SRH的变化,并分析不同因素与SRH之间关联的强度。

设计

横断面研究。

地点

哥德堡H70出生队列研究。

对象

939名个体,提供了1841份观察数据。

方法

每次检查时使用相同问题评估SRH。可能影响SRH的因素包括躯体和精神疾病负担、功能能力、生活满意度和孤独感。肺功能作为身体健康的指标纳入研究。采用描述性统计和二元回归来探讨队列特征、相关因素和SRH。使用广义线性混合模型(GLMM)进行敏感性分析并检验结果的稳健性。

结果

除了85岁时的孤独感和低疾病负担外,各年龄阶段因素与SRH之间均存在关联。高疾病负担在70岁时关联最强,在85岁时最弱。抑郁在85岁时关联最强,在88岁时最低。当同时控制生活满意度时,各年龄之间的关联发生变化,除88岁外,孤独感不再与SRH差相关。70 - 75岁时因素与SRH差之间的关联通常比85 - 88岁时更强。使用GLMM进行的敏感性分析证实了结果的稳健性。

结论

尽管躯体健康状况出现频率更高,但SRH差的比例随年龄下降。相关因素随年龄而异,表明身体因素对年轻老年人的SRH影响更大,而心理社会因素对高龄老年人的SRH影响更大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2518/12023556/db115f73676f/12877_2025_5923_Fig1_HTML.jpg

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