Burns S M, Wyss J M
Brain Res. 1985 Aug 5;340(1):71-7. doi: 10.1016/0006-8993(85)90774-7.
The visceromotor nature of the rat anterior cingulate cortex was investigated by electrically stimulating this area in both anesthetized and awake animals. Initial studies demonstrated that electrical stimulation of any division of the anterior cingulate cortex elicits a significant fall in blood pressure in the sodium pentobarbital-anesthetized rat. Depressor responses were greatest (up to 50% decreases) following stimulation of the ventral third of the anterior cingulate cortex. Heart rate was not altered by cingulate cortex stimulation. In the awake animal, stimulation of previously identified depressor sites in the rostral third of the pregenual cingulate cortex elicited pressor responses. In contrast, stimulation of the caudal third of this cortex elicited depressor responses, and stimulation of the middle third elicited biphasic (pressor followed by depressor) responses. These results indicate that the anterior cingulate cortex is a visceromotor region which may provide a cortical output for the regulation of blood pressure responses associated with learning and or stress.
通过对麻醉和清醒动物的前扣带回皮层进行电刺激，研究了大鼠前扣带回皮层的内脏运动特性。初步研究表明，在前扣带回皮层的任何区域进行电刺激，都会使戊巴比妥钠麻醉的大鼠血压显著下降。在前扣带回皮层腹侧三分之一区域进行刺激后，降压反应最为明显（血压下降高达50%）。扣带回皮层刺激未改变心率。在清醒动物中，刺激膝前扣带回皮层 Rostral 三分之一区域中先前确定的降压位点会引起升压反应。相反，刺激该皮层尾侧三分之一区域会引起降压反应，而刺激中间三分之一区域会引起双相反应（先升压后降压）。这些结果表明，前扣带回皮层是一个内脏运动区域，可能为调节与学习和/或应激相关的血压反应提供皮层输出。
