Kameyama Yuto, Ashizawa Ryota, Honda Hiroya, Fujishima Ichiro, Ohno Tomohisa, Kunieda Kenjiro, Yoshimoto Yoshinobu
Department of Rehabilitation, Hamamatsu City Rehabilitation Hospital, Hamamatsu, Shizuoka, Japan; Division of Rehabilitation Science, Seirei Christopher University Graduate School, Hamamatsu, Shizuoka, Japan.
Department of Rehabilitation, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan.
J Am Med Dir Assoc. 2025 Jul;26(7):105607. doi: 10.1016/j.jamda.2025.105607. Epub 2025 May 12.
This study investigated the association between phase angle (PhA) and physical performance in older patients with stroke, focusing on lower-limb PhA and predicting rehabilitation outcomes.
A retrospective cohort study.
Seventy-one patients with stroke aged ≥65 years at a Japanese rehabilitation hospital.
Bioelectrical impedance analysis was used to measure whole-body PhA, paralyzed side lower-limb PhA, and nonparalyzed side lower-limb PhA. Physical performance was assessed using the Short Physical Performance Battery (SPPB) test at admission and discharge, with subdomains including balance, gait speed, and chair-rise performance. Multiple regression analysis was performed to determine whether different PhAs affected SPPB scores at discharge after adjusting for various potential confounders.
Higher nonparalyzed side lower-limb PhA were significantly associated with better SPPB scores at discharge (β = 0.313, P = .004), and improved balance (β = 0.281, P = .016) and chair-rise performance (β = 0.388, P = .004). Paralyzed side lower-limb PhA was a predictor of total SPPB (β = 0.290, P = .020), but nonparalyzed side lower-limb PhA was more associated with total SPPB. Whole-body PhA was not associated with either total SPPB or any of the SPPB subitems.
Lower-limb PhA, particularly on the nonparalyzed side, is a significant predictor of physical performance in older patients with stroke. Paralyzed side lower-limb PhA plays a role, particularly in predicting walking ability. These findings suggest that site-specific PhA may represent valuable biomarkers for rehabilitation planning and prognostic assessment in patients recovering from subacute stroke events.
本研究调查了老年中风患者的相角（PhA）与身体机能之间的关联，重点关注下肢相角并预测康复结果。
一项回顾性队列研究。
日本一家康复医院的71名年龄≥65岁的中风患者。
采用生物电阻抗分析来测量全身相角、瘫痪侧下肢相角和非瘫痪侧下肢相角。在入院和出院时使用简短身体机能量表（SPPB）测试评估身体机能，子领域包括平衡、步速和从椅子上站起的能力。进行多元回归分析以确定在调整各种潜在混杂因素后，不同的相角是否会影响出院时的SPPB评分。
较高的非瘫痪侧下肢相角与出院时更好的SPPB评分显著相关（β = 0.313，P = .004），以及更好的平衡能力（β = 0.281，P = .016）和从椅子上站起的能力（β = 0.388，P = .004）。瘫痪侧下肢相角是总SPPB的一个预测指标（β = 0.290，P = .020），但非瘫痪侧下肢相角与总SPPB的关联更强。全身相角与总SPPB或任何SPPB子项目均无关联。
下肢相角，尤其是非瘫痪侧的相角，是老年中风患者身体机能的一个重要预测指标。瘫痪侧下肢相角也起作用，特别是在预测步行能力方面。这些发现表明，特定部位的相角可能是亚急性中风事件康复计划和预后评估中有价值的生物标志物。
