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协作护理对60岁及以上患者抑郁症的影响:德国行为激活IMPACT研究的二次分析

Impact of Collaborative Care on Depression in Patients Aged 60+: A Secondary Analysis of the GermanIMPACT Study on Behavioural Activation.

作者信息

Boczor Sigrid, Ashrafi Sanaz, Bjerregaard Frederike, Bleich Christiane, Grochtdreis Thomas, Lühmann Dagmar, Härter Martin, Hölzel Lars, Hüll Michael, Tinsel Iris, Scherer Martin, Kloppe Thomas

机构信息

Department of General Practice and Primary Care, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

School of Medicine, University of Galway, University Road, H91 TK33 Galway, Ireland.

出版信息

Behav Sci (Basel). 2025 Apr 3;15(4):462. doi: 10.3390/bs15040462.

Abstract

Depressive disorders are highly prevalent among older adults (60+) in Europe. Activating these patients was a core component of the GermanIMPACT study, which evaluated collaborative care in a cluster-randomized primary care setting. The intervention group showed a significant improvement in PHQ-9 remission. The aim of this secondary analysis was to investigate which activities were planned and whether their implementation or non-implementation was associated with depressive symptoms (PHQ-9) after 12 months. Behavioural activation data were collected by the care managers. A categorization for activity type (collected as free text) and activity implementation status was developed. The association of successfully implemented activities, planned-not-implemented activities, and the number of activities per patient with the 12-month PHQ-9 total score was calculated using logistic regressions (adjusted for age, gender, living situation/baseline PHQ-9). A total 2188 activities were planned for 136 patients; 66% were successfully implemented. Mean age was 71 (±7) years (78% female; 52% living alone). Activities focusing on "self-care/spirituality" improved the PHQ-9 outcome (OR 1.540; = 0.048), while planned-not-implemented activities overall worsened it (OR 1.16; = 0.007). Patient activation is key to treating depressive symptoms in old age. Particularly 'self-care/spirituality' activities could be planned, and organizational activities should be closely supported.

摘要

抑郁症在欧洲60岁及以上的老年人中极为普遍。促使这些患者行动起来是德国IMPACT研究的核心组成部分,该研究在一项整群随机初级保健环境中评估了协作护理。干预组在PHQ-9缓解方面有显著改善。这项二次分析的目的是调查计划了哪些活动,以及在12个月后这些活动的实施或未实施是否与抑郁症状(PHQ-9)相关。行为激活数据由护理经理收集。制定了活动类型(作为自由文本收集)和活动实施状态的分类。使用逻辑回归计算成功实施的活动、计划但未实施的活动以及每位患者的活动数量与12个月的PHQ-9总分之间的关联(根据年龄、性别、生活状况/基线PHQ-9进行调整)。共为136名患者计划了2188项活动;66%的活动成功实施。平均年龄为71(±7)岁(78%为女性;52%独自生活)。关注“自我护理/精神层面”的活动改善了PHQ-9的结果(OR 1.540;P = 0.048),而计划但未实施的活动总体上使其恶化(OR 1.16;P = 0.007)。患者的行动能力是治疗老年抑郁症状的关键。尤其可以计划开展“自我护理/精神层面”的活动,并且组织活动应得到密切支持。

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