Impact of Kalanchoe ) Supplementation in Goat Maternal Diet on Hepatic and Renal Function and Reproductive Performance.

, a medicinal plant rich in bioactive compounds, has the potential to serve as a feed supplement, reducing reliance on conventional livestock medications while potentially enhancing productivity. This study evaluated the effects of supplementation over 52 days on kidney and liver function, metabolism, weight changes, and reproductive efficiency in multiparous Alpine goats during the breeding season. Fifty-five goats were assigned to either a control (CTL, n = 27; 47.6 ± 1.1 kg) or a -supplemented (KAL, n = 28; 47.6 ± 1.3 kg) diet. The KAL group received at a dry matter-based inclusion rate of 2 kg t of feed, while the CTL group received no supplementation. Blood samples were collected at four time points to assess the biochemical markers of kidney and liver function. Pregnancy was achieved through natural mating, and reproductive efficiency was evaluated. Overall, liver and kidney function did not differ significantly between treatments ( > 0.05). However, KAL supplementation was associated with increased creatinine ( < 0.05), ALP ( < 0.001), and bilirubin ( < 0.05) at specific time points, whereas CTL goats exhibited higher BUN ( < 0.001), AST ( < 0.05), albumin ( < 0.001), total protein ( ≤ 0.05), and phosphorus ( < 0.01) on specific dates. Other metabolic markers, weight gain, and reproductive efficiency did not differ between treatments ( > 0.05). Overall, supplementation had mild, transient effects on goat health without significantly impacting productivity. Further research is needed to explore its long-term effects and optimal dosage for livestock nutrition.