Dalokay Nidai, Sulu Ayse, Kosger Pelin, Kaya Tugba Barsan, Ucar Birsen
Department of Pediatrics, Faculty of Medicine, Eskişehir Osmangazi University, Eskisehir 26040, Turkey.
Department of Pediatric Cardiology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir 26040, Turkey.
Medicina (Kaunas). 2025 Mar 23;61(4):573. doi: 10.3390/medicina61040573.
: This study aimed to evaluate the cardiac functions of 7- to 11-year-old children with a history of preterm birth using echocardiography and to assess the relationship between these functions and neonatal factors. : A total of 64 children were included in the study, consisting of 32 children aged 7 to 11 years with a history of preterm birth and 32 age- and gender-matched term birth controls. : While no significant differences were detected between the preterm and term birth groups regarding age, height, and body weight, echocardiographic data revealed higher values of mitral E, mitral A, and tricuspid A by pulse wave Doppler, as well as septal E by tissue Doppler, in the preterm group compared to the term birth group ( < 0.05). Additionally, the left ventricular global longitudinal peak strain, right ventricular free wall and right ventricular 4-chamber strain, IVRT, MPI, MAPSE, and LVESV values were lower in the preterm group than in the term birth group ( < 0.05). No significant differences were detected in circumferential strain measurements. Right ventricular strain measurements were significantly lower in the preterm group ( = 0.001). : While conventional echocardiographic examinations did not reveal obvious pathological findings in school-age children with a history of preterm birth, further echocardiographic assessments demonstrated differences compared to term birth controls, particularly in diastolic functions and right and left ventricular longitudinal strain measurements.
本研究旨在采用超声心动图评估有早产史的7至11岁儿童的心脏功能，并评估这些功能与新生儿因素之间的关系。本研究共纳入64名儿童，其中包括32名7至11岁有早产史的儿童和32名年龄及性别匹配的足月出生对照儿童。虽然早产组和足月出生组在年龄、身高和体重方面未检测到显著差异，但超声心动图数据显示，与足月出生组相比，早产组的二尖瓣E、二尖瓣A和三尖瓣A的脉冲波多普勒值以及组织多普勒的室间隔E值更高（<0.05）。此外，早产组的左心室整体纵向峰值应变、右心室游离壁和右心室四腔应变、IVRT、MPI、MAPSE和LVESV值低于足月出生组（<0.05）。圆周应变测量未检测到显著差异。早产组的右心室应变测量值显著较低（=0.001）。虽然传统超声心动图检查未在有早产史的学龄儿童中发现明显的病理结果，但进一步的超声心动图评估显示与足月出生对照儿童相比存在差异，特别是在舒张功能以及左右心室纵向应变测量方面。
