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微生物生态毒理学——40年回顾

Microbial Ecotoxicology-40 Years on.

作者信息

Ford Tim

机构信息

Department of Biomedical and Nutritional Sciences, University of Massachusetts Lowell, Lowell, MA 01854-5125, USA.

出版信息

Life (Basel). 2025 Mar 21;15(4):514. doi: 10.3390/life15040514.

Abstract

Although ecotoxicology was emerging as a field through the 1970s, the incorporation of microbial indicators into the framework has been slower to evolve. The exploration of microbes as sensitive toxicity tests began in the late 70s and early 80s (with the emergence of Microtox and other simple tests). However, the applications have been limited, beyond water and wastewater screening. This opinion piece reflects my own perspective on the field-from my early excitement in the 1990s for its possibilities, to a sense of frustration at the slow pace of new development and applications in the field-despite the surge of "omics" options. While microbiology still fails to lead the field of ecotoxicology, the potential remains.

摘要

尽管生态毒理学在整个20世纪70年代逐渐成为一个领域,但将微生物指标纳入该框架的发展却较为缓慢。将微生物用作敏感毒性测试的探索始于70年代末和80年代初(随着Microtox和其他简单测试的出现)。然而,其应用一直局限于水和废水筛选之外。这篇观点文章反映了我对该领域的个人看法——从20世纪90年代我对其可能性的最初兴奋,到尽管有大量“组学”选项,但对该领域新发展和应用的缓慢步伐感到沮丧。虽然微生物学仍未能引领生态毒理学领域,但潜力依然存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f978/12028737/39f85e74e5d7/life-15-00514-g001.jpg

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