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缺铁状态下的脑功能:综述

Cerebral function in iron deficiency: a review.

作者信息

Evans D I

出版信息

Child Care Health Dev. 1985 May-Jun;11(3):105-12. doi: 10.1111/j.1365-2214.1985.tb00455.x.

DOI:10.1111/j.1365-2214.1985.tb00455.x
PMID:4028339
Abstract

Studies in many parts of the world have shown that children with iron deficiency and anaemia show minor defects of cerebral function such as poor attentiveness, poor coordination and slightly impaired scores on developmental assessment. The patients improve rapidly after treatment with iron--too quickly for their anaemia to have been corrected. Such changes have not been detected in children with anaemia from other causes, nor in patients with iron deficiency too slight to cause anaemia. The possibility that these changes are due in some way to some other aspect of malnutrition has not been excluded. Fortunately they are minimal, easily reversible and potentially preventable.

摘要

世界上许多地区的研究表明,缺铁和贫血的儿童存在轻微的脑功能缺陷,如注意力不集中、协调性差以及发育评估得分略有受损。用铁剂治疗后,这些患者恢复迅速——快到贫血尚未得到纠正。在由其他原因导致贫血的儿童中,以及在缺铁程度轻微以至于未导致贫血的患者中,均未检测到此类变化。尚未排除这些变化在某种程度上是由营养不良的其他方面所致的可能性。幸运的是,这些变化很轻微,易于逆转且有可能预防。

相似文献

1
Cerebral function in iron deficiency: a review.缺铁状态下的脑功能:综述
Child Care Health Dev. 1985 May-Jun;11(3):105-12. doi: 10.1111/j.1365-2214.1985.tb00455.x.
2
The effects of therapy on the developmental scores of iron-deficient infants.治疗对缺铁婴儿发育评分的影响。
J Pediatr. 1978 Jan;92(1):21-5. doi: 10.1016/s0022-3476(78)80063-8.
3
[The intelligence quotient and malnutrition. Iron deficiency and the lead concentration as confusing variables].[智商与营养不良。缺铁和铅浓度作为混淆变量]
Bol Med Hosp Infant Mex. 1991 Nov;48(11):826-31.
4
Behavioral alterations in iron deficiency.缺铁时的行为改变。
Adv Pediatr. 1988;35:331-59.
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Behavioral aspects of iron deficiency.缺铁的行为学方面
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Effect of mild iron deficiency on infant mental development scores.轻度缺铁对婴儿智力发育评分的影响。
J Pediatr. 1983 Apr;102(4):519-22. doi: 10.1016/s0022-3476(83)80177-2.
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Long-term developmental outcome of infants with iron deficiency.缺铁婴儿的长期发育结局
N Engl J Med. 1991 Sep 5;325(10):687-94. doi: 10.1056/NEJM199109053251004.
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Iron deficiency in infancy and childhood.
Clin Haematol. 1982 Jun;11(2):339-51.
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Iron deficiency anemia and iron therapy effects on infant developmental test performance.缺铁性贫血及铁剂治疗对婴儿发育测试表现的影响。
Pediatrics. 1987 Jun;79(6):981-95.
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Behavioral alterations in iron deficiency.缺铁时的行为改变。
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引用本文的文献

1
Role of micronutrients for physical growth and mental development.微量营养素对身体生长和智力发育的作用。
Indian J Pediatr. 2004 Jan;71(1):59-62. doi: 10.1007/BF02725658.
2
Iron deficiency anemia in 1-year-old children of disadvantaged families in Montreal.蒙特利尔贫困家庭1岁儿童的缺铁性贫血
CMAJ. 1992 May 1;146(9):1571-7.