Corona-España Ana Montserrat, García-Ramírez Mario Alberto, Rodríguez-Buenfil Ingrid Mayanin, Delgado-Saucedo Jorge Iván, González-Reynoso Orfil
Department of Chemistry, University Center of Applied Sciences and Engineering, University of Guadalajara, Guadalajara 44430, Mexico.
Department of Electro-Photonic Engineering, University Center of Applied Sciences and Engineering, University of Guadalajara, Guadalajara 44430, Mexico.
Pharmaceutics. 2025 Mar 28;17(4):437. doi: 10.3390/pharmaceutics17040437.
The genus contains more than 300 species where garlic, onion and leek can be found. Recent studies highlight the potential of phytochemicals present in the genus as therapeutic agents, such as antimicrobial, antihypertensive, antioxidant and antiinflammatory, which makes it a widely studied genus and an attractive option for both the pharmaceutical and food industries. This review aims to explore the current knowledge in this field. It highlights key findings regarding the pharmacological approach on thiosulfinates and polysulfides for , and species. Further, by integrating what has been reported in previous research, this review proposes an action mechanism for the formation of thiosulfinates and polysulfides, which will help harness the therapeutic potential of nature-inspired solutions in combating illness.
该属包含300多种植物，其中包括大蒜、洋葱和韭菜。最近的研究强调了该属植物中存在的植物化学物质作为治疗剂的潜力，如抗菌、抗高血压、抗氧化和抗炎作用，这使其成为一个被广泛研究的属，也是制药和食品行业有吸引力的选择。本综述旨在探索该领域的现有知识。它突出了关于硫代亚磺酸盐和多硫化物对该属不同物种的药理学研究的关键发现。此外，通过整合先前研究中已报道的内容，本综述提出了硫代亚磺酸盐和多硫化物形成的作用机制，这将有助于利用受自然启发的解决方案在对抗疾病方面的治疗潜力。
