角膜内皮感染

Infections of the Corneal Endothelium.

作者信息

Wang Jessie, Rabiee Behnam, Patel Chandani, Jafri Mansab, Hussain Hamad, Chaudhry Aaila, Chaudhry Imtiaz, Kamoun Layla, Chaudhry Iftikhar, Oh Lewis, Bobat Fatima I, Shukla Deepak, Farooq Asim V

机构信息

Duke Eye Center, Duke University, Durham, NC 27705, USA.

Department of Ophthalmology, Nazareth Hospital, Trinity Health Mid-Atlantic, Philadelphia, PA 19152, USA.

出版信息

Microorganisms. 2025 Mar 28;13(4):778. doi: 10.3390/microorganisms13040778.

DOI:10.3390/microorganisms13040778

PMID:40284615

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12029634/

Abstract

Corneal endotheliitis is an inflammatory process, most commonly of viral etiology, that manifests clinically with features including corneal edema, keratic precipitates, and a mild anterior chamber reaction. Several studies have implicated human herpesviruses from the family as primary causes of corneal endotheliitis, including cytomegalovirus (CMV), varicella zoster virus (VZV), and herpes simplex viruses 1 and 2 (HSV-1 and HSV-2). This review critically evaluates the present literature surrounding herpesvirus infections of the corneal endothelium.

摘要

角膜内皮炎是一种炎症过程，最常见的病因是病毒感染，临床症状包括角膜水肿、角膜后沉着物和轻度前房反应。多项研究表明，疱疹病毒科的人类疱疹病毒是角膜内皮炎的主要病因，包括巨细胞病毒（CMV）、水痘带状疱疹病毒（VZV）以及单纯疱疹病毒1型和2型（HSV-1和HSV-2）。本综述对目前有关角膜内皮疱疹病毒感染的文献进行了批判性评估。