Symeonidou Isaia, Sioutas Georgios, Gelasakis Athanasios I, Beugnet Frederic, Papadopoulos Elias
Laboratory of Parasitology and Parasitic Diseases, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Laboratory of Farm Animal Anatomy and Physiology, Department of Animal Science and Aquaculture, School of Agricultural Production, Infrastructure and Environment, Agricultural University of Athens, 11855 Athens, Greece.
Vet Sci. 2025 Apr 19;12(4):385. doi: 10.3390/vetsci12040385.
Feline parasitism affects animals' health and welfare. Faeces from 472 client-owned cats from Greece were examined to provide updated data on the epizootiology of metazoan endo- and ectoparasites (namely, , Ancylostomatidae, , lungworms, , , fleas, ticks and ). All positive animals received a topical formulation containing esafoxolaner, eprinomectin and praziquantel (NexGard Combo, Boehringer Ingelheim), and its efficacy was evaluated. The overall prevalence of parasitism was 22.9%, while that of multiparasitism was 16.3%. (18.4%) was the most prevalent endoparasite, followed by Ancylostomatidae (10.8%), (4.7%), lungworms (2.5%) and (0.4%). Regarding ectoparasites, (3.2%), fleas (2.3%), ticks (0.6%) and (0.4%) were found. To estimate the efficacy of treatment, the geometric means of the number of parasitic elements before the first treatment and post-treatment, (i) 14 days for intestinal helminths, (ii) 28 and 56 days for lungworms and (iii) 28 days for and fleas, were estimated and compared. Following statistical analyses (paired -test and McNemar's test), an efficacy of 100% was recorded against the most commonly detected parasites (gastrointestinal helminths and mites) and a notable statistically significant effect against fleas and lungworms after one dose, while 100% efficacy against lungworms was achieved after two doses of the product. No adverse effects were reported. The prevalence of parasitism in owned cats in Greece remains high, highlighting the demand for targeted preventive antiparasitic schemes. This study demonstrated high-level efficacy and tolerance of NexGard Combo against common endoparasites and ectoparasites of household cats in Greece.
猫寄生虫病会影响动物的健康和福利。对来自希腊的472只客户拥有的猫的粪便进行了检查，以提供有关后生动物体内和体外寄生虫（即钩口科、肺线虫、、跳蚤、蜱虫和）流行病学的最新数据。所有检测出寄生虫的动物都接受了一种含有依沙氟拉钠、埃普利诺菌素和吡喹酮的局部用制剂（福来恩驱虫组合，勃林格殷格翰公司），并对其疗效进行了评估。寄生虫感染的总体患病率为22.9%，而多重寄生虫感染的患病率为16.3%。（18.4%）是最常见的体内寄生虫，其次是钩口科（10.8%）、（4.7%）、肺线虫（2.5%）和（0.4%）。关于体外寄生虫，发现了（3.2%）、跳蚤（2.3%）、蜱虫（0.6%）和（0.4%）。为了评估治疗效果，估计并比较了首次治疗前和治疗后寄生虫数量的几何平均值，（i）肠道蠕虫为14天，（ii）肺线虫为28天和56天，（iii）和跳蚤为28天。经过统计分析（配对t检验和 McNemar检验），记录到该制剂对最常见的检测到的寄生虫（胃肠蠕虫和螨虫）的疗效为100%，对跳蚤和肺线虫在一剂后有显著的统计学显著效果，而在两剂该产品后对肺线虫的疗效达到100%。未报告不良反应。希腊家养猫的寄生虫感染患病率仍然很高，突出了对有针对性的预防性抗寄生虫方案的需求。这项研究证明了福来恩驱虫组合对希腊家猫常见的体内和体外寄生虫具有高效和耐受性。
