Perestrelo Gonçalo, Velho Pedro, Macedo Eugénia A
Laboratory of Separation and Reaction Engineering-Laboratory of Catalysis and Materials (LSRE-LCM), Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.
Associate Laboratory in Chemical Engineering (ALiCE), Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.
Molecules. 2025 Mar 30;30(7):1532. doi: 10.3390/molecules30071532.
Food waste remains a critical global concern, with approximately one third of all food produced being ultimately discarded. Therefore, it is urgent to develop new techniques for the effective repurpose of waste. Aqueous two-phase systems (ATPSs) stand out as a simple and biocompatible liquid-liquid extraction technique for the recovery of bioactive substances from food waste. In ATPSs, the target species partition between two liquid phases, according to affinity, which facilitates its extraction. This work aimed at extracting three polyphenols-chlorogenic acid (CA), ferulic acid (FA), and resveratrol (RV)-through the application of eco-friendly ATPSs composed of water, ethyl lactate (EL), and organic salts, namely disodium succinate (NaSuccinate) and disodium tartrate (NaTartrate), for future application in the valorisation of food waste. All partitions presented successful results, with values of partition coefficients () higher than 1 and extraction efficiencies () higher than 50%, indicating a preferential migration of the polyphenols to the top phase. The extraction of FA using the ATPS based on NaTartrate presented the most promising results, with = 19 ± 6 and = (94.2 ± 0.9)% for the longest tie-line. Additionally, a comparison with previous works of the research group was drawn, with the extraction of RV exhibiting outstanding performance across all studied ATPSs. Therefore, the assessed ATPSs were shown to hold immense potential for the recovery of polyphenols.
食物浪费仍然是一个关键的全球问题，所有生产的食物中约有三分之一最终被丢弃。因此，开发有效再利用废物的新技术迫在眉睫。双水相体系（ATPSs）作为一种简单且生物相容的液-液萃取技术脱颖而出，可用于从食物废物中回收生物活性物质。在双水相体系中，目标物质根据亲和力在两个液相之间分配，这有利于其萃取。这项工作旨在通过应用由水、乳酸乙酯（EL）和有机盐（即丁二酸钠（NaSuccinate）和酒石酸钠（NaTartrate））组成的环保型双水相体系来提取三种多酚——绿原酸（CA）、阿魏酸（FA）和白藜芦醇（RV），以便未来应用于食物废物的增值利用。所有分配都取得了成功，分配系数（）值高于1，萃取效率（）高于50%，表明多酚优先迁移到上相。使用基于酒石酸钠的双水相体系萃取阿魏酸呈现出最有前景的结果，对于最长的系线， = 19 ± 6且 = (94.2 ± 0.9)%。此外，与该研究小组之前的工作进行了比较，白藜芦醇的萃取在所有研究的双水相体系中都表现出优异的性能。因此，所评估的双水相体系显示出在回收多酚方面具有巨大潜力。
