Yee R W, Matsuda M, Schultz R O, Edelhauser H F
Curr Eye Res. 1985 Jun;4(6):671-8. doi: 10.3109/02713688509017661.
Human endothelial morphologic changes were quantitated by specular microscopy and computer-assisted morphometry to establish normal baselines of various morphologic parameters. Cellular polymegethism and cellular pleomorphism increases with age, and normal baseline parameters are detailed. Furthermore, no significant difference in any morphologic parameters between the right and left eye and between central and peripheral endothelium was detected in the normal corneas examined. These normal morphologic baselines can possibly be utilized to detect early corneal endothelial pathology and/or cell loss nondetectable by cell density measurement.
通过镜面显微镜和计算机辅助形态测量法对人类内皮细胞形态变化进行定量分析，以建立各种形态学参数的正常基线。细胞大小不均和细胞多形性随年龄增长而增加，并详细说明了正常基线参数。此外，在所检查的正常角膜中，未检测到右眼和左眼之间以及中央和周边内皮细胞之间在任何形态学参数上有显著差异。这些正常形态学基线可能有助于检测早期角膜内皮病变和/或通过细胞密度测量无法检测到的细胞丢失。
